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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
publication
Title:
WHO Food Additive Series 35: 4-Hexylresorcinol (136-77-6)
Year:
1983
Bibliographic source:
http://www.inchem.org/documents/jecfa/jecmono/v35je04.htm

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no guideline provided
GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
4-hexylresorcinol
EC Number:
205-257-4
EC Name:
4-hexylresorcinol
Cas Number:
136-77-6
Molecular formula:
C12H18O2
IUPAC Name:
4-hexylresorcinol

Method

Species / strain
Species / strain / cell type:
S. typhimurium, other: TA98, TA100, TA1535, TA1537, TA1538
Metabolic activation:
with and without
Test concentrations with justification for top dose:
0-30 µg/plate

Results and discussion

Test results
Species / strain:
S. typhimurium, other: TA98, TA100, TA1535, TA1537, TA1538
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified

Applicant's summary and conclusion