Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-849-3 | CAS number: 86404-04-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Explosiveness
Administrative data
- Endpoint:
- explosiveness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Deviations:
- yes
- Remarks:
- The thermal stability was determined by differential thermal analysis DSC (Differential Scanning Calorimetry).
- GLP compliance:
- no
Test material
- Reference substance name:
- (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2,5-dihydrofuran-2-one
- EC Number:
- 617-849-3
- Cas Number:
- 86404-04-8
- Molecular formula:
- C8H12O6
- IUPAC Name:
- (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-2,5-dihydrofuran-2-one
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Small-scale preliminary testsopen allclose all
- Parameter:
- other: More sensitive to shock than m-dinitrobenzene
- Remarks:
- migrated information
- Remarks on result:
- not measured/tested
- Parameter:
- other: More sensitive to friction than m-dinitrobenzene
- Remarks:
- migrated information
- Remarks on result:
- not measured/tested
- Parameter:
- other: Explosive under influence of flame
- Remarks:
- migrated information
- Remarks on result:
- not measured/tested
- Parameter:
- other: Explosive (not specified)
- Remarks:
- migrated information
- Remarks on result:
- negative (not further specified)
Any other information on results incl. tables
The thermal stability was determined by differential thermal analysis DSC (Differential Scanning Calorimetry). Samples of the test item and of a reference material (empty crucible) are subjected to the same controlled temperature programme. When the test substance undergoes a phase transition or decomposition the corresponding change of enthalpy gives an endothermic (melting) or exothermic (caused by freezing or decomposition) departure from the base line of the temperature record.
Results (scan with 4°C/min)
Sample | Description | Fig. | Thermal signal Range [°C]Peak-temperature [°C] | Energy [kJ/kg] |
917181.13.0544.01LIMS Nr. 21364 | lot: LT005923 | 1a | Endo: 106 -121,112Exo: 239 -318,289 | -128520 |
ídem | idem | 1b | Endo: 106 - 123, 113Exo: 236 - 323, 289 | -126516 |
Applicant's summary and conclusion
- Interpretation of results:
- non explosive
- Remarks:
- Migrated information
- Conclusions:
- As stated in the reference (Commission Regulation (EC) No 440/2008, Annex A.14, § 1.1) “the tests need not to be performed when available thermodynamic information (e.g. heat of formation, heat of decomposition) and/or absence of certain reactive groups in the structural formula establishes beyond reasonable doubt that the substance is incapable of rapid decomposition with evolution of gases or release of heat (i.e. the material does not present any risk of explosion).”
1. The determination of the thermal stability of the test substance by DSC (Differential Scanning Calorimetry) - Figures 1 a/b show that between 30°C and 400°C the exothermal decomposition energy is about 518 kJ/kg and therefore slightly above the limit of 500 kJ/kg for exclusion given in the Regulation (EC) No 1272/2008 (CLP) of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, Chapter 2.1.4.3. (c).
2. According to the chemical structure and the list of reactive groups that could have explosive properties in Bretherick’s Handbook of Reactive Chemical Hazards, Butterworths, 4th edition, it can be excluded that the tested substance has explosive properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.