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Diss Factsheets
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EC number: 213-551-9 | CAS number: 976-56-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
There is a high probability that the product is not acutely harmful to aquatic algae.
Based on long-term (chronic) toxicity study data, the product is very likely not harmful to aquatic algae.
Key value for chemical safety assessment
Additional information
To assess the growth inhibition potential of the test substance on aquatic algae, a study was conducted according to the algal growth inhibition test guideline described in 87/302/EEC. Green Algae (Scenedesmus subspicatus) were used in an initial cell density of 10300 cells/mL. Tween 20 was used as a vehicle. The tested concentrations were 1.23, 3.7, 11, 33 and 100 mg test substance/L (nominal). Each test concentration was tested in 3 replicates, the blank control in 6. The duration of the test was 72 hours, cell densities were counted after 24, 48 and 72 hours. The mean cell densities at the end of the exposure time (72 hours) were 355000 cells/mL for the blank control and 284000 for the vehicle control. For the test concentrations, the following cell densities were determined: test conc. 1.23 mg/L: 418000 cells/mL, test conc. 37000 mg/L: 409000 cells/mL, test conc. 11 mg/L: 249000 cells/mL, test conc. 33 mg/L: 309000 cells/mL and test conc. 100 mg/L: 98000 cells/mL. As a result, the EbC50 value was determined to be 62 mg/L and the NOEbC was determined to be 3.7 mg/L. No values based on growth rate were availble.
As supporting information a study with CAS 65140-91-2 was conducted. In a 72 hour acute toxicity study, the green algae Scenedesmus subspicatus was exposed to the test item at nominal concentrations of 1.23, 3.7, 11, 33, 100 mg/L under static conditions in accordance with the EEC guideline 302/87 (1987). The NOEbC and EbC50 values based on cell number were both above 100 mg/L. The detailed read across justification is attached to the endpoint study record.
In conclusion, there is a high probability that the product is not acutely harmful to aquatic algae. Based on long-term (chronic) toxicity study data, the product is very likely not harmful to aquatic algae.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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