Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 219-058-5 | CAS number: 2344-80-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD Guideline Study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Chloromethyltrimethylsilane
- EC Number:
- 219-058-5
- EC Name:
- Chloromethyltrimethylsilane
- Cas Number:
- 2344-80-1
- Molecular formula:
- C4H11ClSi
- IUPAC Name:
- (chloromethyl)trimethylsilane
- Test material form:
- other: colourless liquid
- Details on test material:
- Purity 99.8%
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Activated sludge (micro organisms from a domestic waste
water treatment plant) was supplied by sewage plant Rossdorf,
Germany.
The activated sludge used for this study was washed by centrifugation
and the supematant liquid phase was decanted. The
solid material was re-suspended in tap water and again centrifuged.
This procedure was repeated twice.
An aliquot of the final sludge suspension was weighed, dried
and the ratio of wet sludge to its dry weight was determined.
Based on this ratio, calculated aliquots of washed sludge suspension,
corresponding to 4 g dry material per litre were
mixed with test water (see 6.5) and then aerated until use. Before
use the sludge was filtered through cotton wool. - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- ca. 5.22 mg/L
- Based on:
- ThOD/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Surrounding Type: Controlled environment room
Temperature: 21.1 - 21.8 °C
Light Conditions: Darkness
pH-Value of Test Water: 7.6 (measured at the start of the test)
Oxygen Concentration of Test Water: 8.8 - 9.0 mg OiL (measured at the start of the test)
Reference substance
- Reference substance:
- benzoic acid, sodium salt
- Remarks:
- Sodium benzoate 5.96 /!L/L corresponding to 5.24 mg/L corresponding to a theoretical oxygen demand of 10.25 mg/L (based on ThOD of 1.956 mg oxygen per mg test item)
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 6
- Sampling time:
- 28 d
- Details on results:
- Under the test conditions the percentage biodegradation of
Silane CMM3 reached 6% (mean value) after 28 days of
incubation.
BOD5 / COD results
- Results with reference substance:
- The reference item sodium benzoate as sufficiently degraded
to a mean of 61% after 2 days, and to a mean of
77% after 28 days of incubation, thus confirming the suitability
of the used activated sludge inoculum.
The percentage biodegradation of the reference item confirms
the suitability of the used activated sludge inoculum.
Any other information on results incl. tables
In the toxicity control containing both, the test item and the reference item sodium benzoate, a mean of 42% biodegradation was noted within 14 days and 39% biodegradation after 28 days of incubation.
According to the test guidelines the test item can be assumed not to be inhibitory on the activated sludge micro organisms because degradation was> 25 % within 14 days.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- Under the test conditions the percentage biodegradation of Silane CMM3
reached 6 % (mean value) after 28 days of incubation.
The test item can therefore be considered not to be readily biodegradable. - Executive summary:
The test item Silane CMM3 was investigated for its ready biodegradability in a Closed Bottle Test over a period of 28 days. The biodegradation was followed by the oxygen uptake of the micro organisms during exposure. A reference item was tested simultaneously under the same conditions as the test item, and functioned as a procedure control. Degradation rate of test item calculated by the oxygen consumption of the activated sludge microorganisms after 28 days of incubation.
Under the test conditions the percentage biodegradation of Silane CMM3 reached 6 % (mean value) after 28 days of incubation. The test item can therefore be considered not to be readily biodegradable.
The reference item sodium benzoate was sufficiently degraded to a mean of 61 % after 2 days, and to a mean of 77 % after 28 days of incubation, thus confirming the suitability of the used activated sludge inoculum. In the toxicity control containing both, the test item and the reference item sodium benzoate, a mean of 42 % biodegradation was noted within 14 days and 39 % biodegradation after 28 days of incubation. Thus, the test item can be assumed to be not inhibitory on the activated sludge micro orgamsms. page
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.