Registration Dossier
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EC number: 203-766-6 | CAS number: 110-42-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h) > 0.055 mg/L (experimental, measured average concentration) for Pseudokirchnerella subcapitata (OECD 201)
NOEC (72 h) = 0.055 mg/L (experimental, measured average concentration) for Pseudokirchnerella subcapitata (OECD 201)
EC50 (96 h)= 1.35 mg/L (QSAR calculation)
Key value for chemical safety assessment
Additional information
One study evaluating the toxicity of methyl decanoate (CAS No. 110-42-9) to algae is available (Bouwman, 2010). This test was conducted according to OECD Guideline 201, under GLP conditions. Pseudokirchnerella subcapitata was exposed to the test substance for 72 hours within static water regime at 23 ± 1°C. Measurements of test concentrations (loading rate at 100 mg/L and dilutions) were performed through GC analysis. After 72 hours, no significant effects on algal growth rate were reported except for the highest concentration (0.055 mg/L, measured initial average concentration), in which 28.5% inhibition was observed. The ErC50 (72 h) was determined to be > 0.055 mg/L and the NOErC (72 h) = 0.055 mg/L. Additionally, a QSAR calculation (ECOSAR v1.00) was performed, resulting in an EC50 (96 h) of 1.35 mg/L (green algae, calculation for neutral organics).
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