Registration Dossier
Registration Dossier
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EC number: 201-204-4 | CAS number: 79-41-4
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Rationale for reliability incl. deficiencies:
- other: Special test procedure.
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicological and Pharmacological Actions of Methacrylate.
- Author:
- Mir GN, Lawrence WH, Autian J
- Year:
- 1 974
- Bibliographic source:
- J. Pharm. Sci. 63: 376 - 381
Materials and methods
- Type of study / information:
- other: Heart/Blood-circulation
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methacrylic acid
- EC Number:
- 201-204-4
- EC Name:
- Methacrylic acid
- Cas Number:
- 79-41-4
- Molecular formula:
- C4H6O2
- IUPAC Name:
- methacrylic acid
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- details not given
Results and discussion
Any other information on results incl. tables
abrupt fall followed by a secondary rise in
blood pressure, increased respiratory rate,
decreased heart rate and electrocardiographic changes.
LD = 0.1 g/kg
= 100 mg/kg
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
