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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

A test with activated sludge with a duration of 3 hours was performed according to ISO 8192 (Test for Inhibition of Oxygen Consumption by Activated Sludge). An EC50 of 420 mg/L related to the concentration of N-(1,3-dimethylbutyl)-N'-phenylbenzene-1,4-diamine was observed (Currenta 2012).

Key value for chemical safety assessment

EC50 for microorganisms:
420 mg/L

Additional information

Two studies performed with p-hydroquinone, a secondary hydrolysis product of 6PPD, show that this substance is relatively toxic to organisms (NOEC 1 mg/L, IC50 71 mg/L).