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Diss Factsheets
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EC number: 241-234-5 | CAS number: 17194-00-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Results are based on nominal values, and test did not exacty follow existing guidance (1972-study), but followed test method well described and test conditions (eg.g. test medium composition) were properly identified.
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Not a guideline study but meets generally accepted scientific standards and methodology is well documented and described
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain: laboratory clone
- Source: University of Michigan
- Age at study initiation (mean and range, SD): 12h +/- 12h
- Feeding during test: no - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 45.2 mg/L as CaCO3
- Test temperature:
- 18 +/- 1 °C
- pH:
- 7.74
- Dissolved oxygen:
- +/- 9 mg O2/L
- Salinity:
- not reported
- Nominal and measured concentrations:
- nominal/measured test concentrations not reported: geometric series of 5-12 concentrations (not specified for Ba)
- Details on test conditions:
- TEST SYSTEM
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates):2
- No. of vessels per control (replicates): not reported
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Lake Superior water; unfiltered water strained through a #20 bolting cloth. Chemical characteristics of Lake Superior water were monitored during the testing period according to procedures outlined by the American Public Health Association and procedures employing atomic absorption spectroscopy.
- Metals: 14 µg Ba/L ; 16 µg Sr/L ; 0.78 µg Zn/L ; <0.5 µg Ni/L ; 1.51 µg Cu/L ; <0.5 µg Co/L ; < 0.01 g Hg/L ; < 0.1 µg Cd/L
- Chloride: 1.22 mg/L
- Alkalinity: 42.3 mg/L as CaCO3
- Ca: 13.7 mg /L
- Mg: 3.12 mg/L
- K: 0.53 mg/L
- Na: 1.13 mg/L
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): complete immobilisation or death - Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 14 500 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- as barium
- Basis for effect:
- mortality
- Remarks:
- including immobility
- Reported statistics and error estimates:
- Results were statistically evaluated with the method of Litchfield and Wilcoxon (1949). LC50 was used for survival and represents an interpolation from three or more partial-effect concentrations.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 48h-LC50 for Daphnia magna exposed to barium chloride dihydrate was found to be 14.5 mg Ba/L.
- Executive summary:
An acute toxicity test with barium chloride dihydrate to Daphnia magna was realized according to non standardised method with no GLP statement. However the test method is well described and the test conditions were properly identified. This test is part of a serie of similar tests on daphnids performed in 1972 by Biesinger and Christensen. A full study was performed under static conditions. The treatment and control groups had two replicates, each containing 10 daphnids and the test duration was 48 hours. The results are based on nominal concentrations. The 48h-LC50 for Daphnia magna is reported as 14.5 mg Ba/L.
Reference
Description of key information
A reliable, nominal 48h-EC50 of 14.5 mg Ba/L has been reported by Biesinger and Christensen (1972), using the cladoceran Daphnia magna as test organism.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- LC50
- Effect concentration:
- 14.5 mg/L
Additional information
The reported 48h-LC50 of 14.5 mg Ba/L by Biesinger and Christensen (1972) for Daphnia magna is based on nominal test concentrations, using the soluble barium chloride dihydrate as test substance. The followed test procedure in this 1972 -study was well described and test conditions (e.g. test medium composition) were properly identified.
No reliable data were identified for the marine compartment
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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