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Henry's Law constant

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Reference
Endpoint:
Henry's law constant
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented publication which meets basic scientific principles
Qualifier:
no guideline available
Principles of method if other than guideline:
Determination of thermodynamic Henry's law constants by equilibrium partial pressure measurements over aqueous solutions at 298.15 K
GLP compliance:
no
H:
1 130 other: mol/atm kg
Temp.:
25 °C

The reported value is equivalent to 8.85E-7 atm m³/mol.

Conclusions:
For isobutyric acid, an experimetal HLC of 8.84E-7 atm m³/mol was determined in a study according to accepted scientific principles
Executive summary:

For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 (25°C).

Description of key information

measured HLC (25°C) = 8.85E-7atm*m3/mol (0.08967 Pa*m3/mol) (method: equilibrium partial pressure measurements over aqueous solutions)

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
0.09
at the temperature of:
20 °C

Additional information

For isobutyric acid, a Henry's law constant of 8.85E-7 atm m³/mol was determined in a study using equilibrium partial pressure measurements over aqueous solutions at 298.15 K (25°C) (Khan, 1992).

 

A calculated Henry's law constant of 9.65E-007 atm*m3/mol (bond contribution method) and of 9.09E-007 atm*m3/mol (group contribution method) was obtained using the program HENRYWIN v 3.2 (Part of US EPA EPI Suite v4.00) (ECT, 2009). Measured and calculated HLC match satisfactorily.

 

Isobutyric acid volatilizes only to a low degree from water.