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Diss Factsheets
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EC number: 202-267-0 | CAS number: 93-68-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The key study was conducted in year 2008 and reported in year 2009 according to the OECD Guideline for the testing of chemicals 301 F and
principles of GLP.
The first test item replicate reached the 10% level (beginning of biodegradation) after 3 days and the pass level of 60% after 10 days. The biodegradation came to a maximum of 97% on day 23. The second test item replicate reached the 10% level after 4 days and the pass level of 60% after 8 days. The biodegradation came to a maximum of 93% on day 24. The mean biodegradation rate after 28 days was 92%.
Therefore, the test item must be regarded as readily biodegradable in the 10-d-window and after 28 days.
Testing of 2‘-methylacetoacetanilide for inherent biodegradability was performed in the Zahn-Wellens test in the year 1989. The supporting study report was newly generated from archieved laboratory manuscripts. The results of testing the biodegradability in the Zahn-Wellens test revealed that: 2‘-Methylacetoacetanilide is inherently, completely and rapidly biodegradable. The results of this test are only valid tor the tested batch.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
In the key study the first test item replicate reached the 10% level (beginning of biodegradation) after 3 days and the pass level of 60% after 10 days. The biodegradation came to a maximum of 97% on day 23. The second test item replicate reached the 10% level after 4 days and the pass level of 60% after 8 days. The biodegradation came to a maximum of 93% on day 24. The mean biodegradation rate after 28 days was 92%.
The validity criteria of the guideline are fulfilled.
Therefore, the test item is readily biodegradable in the 10 -d-window and after 28 day
In the supporting study an inherent biodegradability test (Zahn-Wellens) was performed in the year 1989.
The report was newly generated from archieved laboratory manuscripts. The criteria for the evaluation as inherently biodegradable according to the definitions for inherent biodegradability in the OECD Guidelines for Testing of Chemicals were mentioned in the chapter ‘Principles of the test procedure. The results of testing the biodegradability in the Zahn-Wellens test revealed that: 2‘-Methylacetoacetanilide is inherently, completely and rapidly biodegradable. The results of this test are only valid tor the tested batch.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.