Registration Dossier
Registration Dossier
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EC number: 239-346-4 | CAS number: 15307-79-6
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 3.2.1988 - 2.3.1988
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Diclofenac-diethylammonium
- IUPAC Name:
- Diclofenac-diethylammonium
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- mixture of sewage, soil and natural water
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (DOC removal)
- Value:
- 28
- Sampling time:
- 28 d
- Details on results:
- Degradation kinetic:
Day 7: 0%
Day 14: 14%
Day 21: 23%
Day 28: 28%
BOD5 / COD results
- Results with reference substance:
- 97% after 14 days
Applicant's summary and conclusion
- Interpretation of results:
- other: not readily biodegradable
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