Registration Dossier
Registration Dossier
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EC number: 277-362-3 | CAS number: 73296-89-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72h EC50 (Desmodesmus subspicatus, growth rate) > 20 mg/L (nominal, EU Method C.3)
72h EC10 (Desmodesmus subspicatus, growth rate) = 5.4 mg/L (nominal, EU Method C.3)
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 20 mg/L
- EC10 or NOEC for freshwater algae:
- 5.4 mg/L
Additional information
Since no reliable aquatic algae test is available for C12-16AS Na (CAS 73296-89-6), in accordance to Regulation (EC) 1907/2006 Annex XI, 1.5, a read-across to other structurally related category member was conducted. Read-across data from the following substances were used C12-14AS Na (CAS 85586-07-8) and C12-18AS Na (CAS 68955-19-5). Toxicity of alkyl sulfates is dependent on the carbon chain length and the influence of the counter ion can be neglected.
Toxicity of the C12-14AS Na (CAS 85586-07-8) on aquatic algae was investigated in a GLP study with Desmodesmus subspicatus according to EU Method C.3 (Scholz, Elementis, 1995). The study resulted in the 72-hour EC50 value for growth rate of above 20 mg/L. The corresponding 72-hour EC10 for growth rate was 5.4 mg/L. This test is regarded as key study and these values are expected to be a realistic also for C12-16AS Na (CAS 73296-89-6).
One GLP-study is available for C12-18AS Na (CAS 68955-19-1). The study of Scholz (1997) was conducted according to the EU method C.3 with Desmodesmus subspicatus. The EC50 value for growth rate reported after 72 h of exposure was 20 mg/L. The 72-hour EC10 value was 7.6 mg/L.
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