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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 June 2010-13 September 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: This study has been performed according to OECD and EC guidelines and according to GLP principles.
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Conclusions:
The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Lowinox® AH25.
The vapour pressure of the test substance at 20°C (293K) was 7.55 x 10-5 Pa = 5.67 x 10-7 mm Hg.
Executive summary:

The aim of the study was to determine the following physico-chemical properties for Lowinox® AH25: Vapour pressure in accordance with the following guidelines:

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.1 04: "Vapour Pressure", March 23, 2006.

European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: "Vapour Pressure", Official Journal of the European Union no. L220, August 24, 2009.

 

The vapour pressure of the test substance at 20 °C (PT. 20) was determined using the isothermal thermogravimetric effusion method. This method is validated in the range 10-8- 103Pa using a set of reference substances with known vapour pressures. The validity of the method was verified maximum one month before this study using a suspension of hexachlorobenzene {>99%, Fluka Chemie, Buchs, Switzerland) in chloroform (Labscan, Dublin, Ireland) as a reference control substance. The logarithm of its evaporation rate at 20 °C (log vT, 20) deviated < 10% from the average value obtained during the validation test. From this, it was possible to apply the data of the reference substances for the determination of the vapour pressure of the test substance.

 

The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Lowinox® AH25.

The vapour pressure of the test substance at 20 °C (293K) was 7.55 x 10-5Pa = 5.67 x 10-7mm Hg.

Description of key information

The vapour pressure of the test substance at 20 °C (293K) was 7.55 x 10-5Pa = 5.67 x 10-7mm Hg.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information

The vapour pressure of the test substance at 20 °C (PT. 20) was determined using the isothermal thermogravimetric effusion method. This method is validated in the range 10-8- 103 Pa using a set of reference substances with known vapour pressures. The validity of the method was verified maximum one month before this study using a suspension of hexachlorobenzene {>99%, Fluka Chemie, Buchs, Switzerland) in chloroform (Labscan, Dublin, Ireland) as a reference control substance. The logarithm of its evaporation rate at 20 °C (log vT, 20) deviated < 10% from the average value obtained during the validation test. From this, it was possible to apply the data of the reference substances for the determination of the vapour pressure of the test substance.

 

The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Lowinox® AH25.

The vapour pressure of the test substance at 20 °C (293K) was 7.55 x 10-5Pa = 5.67 x 10-7mm Hg.