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EC number: 244-169-0 | CAS number: 21049-70-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The test substance is acutely harmful to aquatic organisms.
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
The test substance consists of 2-(methylamino)ethanol and sulphur dioxide. Since only aquatic studies on fish and Daphnia magna are available for the test substance, the aquatic toxicity of 2-(methylamino)ethanol, compound with sulphur dioxide to algae has been assessed by evaluating the toxic effects of both test substance compounds separately in a read-across approach.
The acute toxicity of 2-(methylamino)ethanol, compound with sulphur dioxide to the fish species Leuciscus idus was found to be > 500 mg/L after 96 h whereas the examination of toxic effects to Daphnia magna resulted in an EC50 of 70.7 mg/L after 48 hours.
Effects of the read-across substances to fish and Daphnia were found to be in the same ranges as the original test substance. Toxicity testing with 2-(methylamino)ethanol (CAS 109-83-1) resulted in an EC50 (48 h) of 33 mg/L while the fish test revealed an LC50 (96 h) of > 100 mg/L. Similar results were retrieved from toxicity testing with the sulphite category members: a study on short-term toxicity to fish resulted in a LC50 > 100 mg SO32-/L and testing with aquatic invertebrates resulted in an EC50 of 74.9 mg SO32-/L.
Aquatic plants turned out to be the most sensitive organisms during toxicity testing with 2-(methylamino) ethanol and sodium sulphite alike, resulting in ErC50 values of 28.1 mg/L and 36.8 mg SO32-/L, respectively.
Concerning long-term toxicity, the hazard assessment is based on information retrieved from the read-across substances sodium sulphite (CAS 7757-83-7) and disodium disulphite (CAS 7681-57-4). The studies which asses chronic toxicity to fish and Daphnia both provide NOECs > 1 mg SO32 -/L.
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