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EC number: 610-962-9 | CAS number: 5311-05-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 2001
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Reference Type:
- other: Draft Renewal Assessment Report under Regulation (EC) 1107/2009
- Title:
- Draft Renewal Assessment Report under Regulation (EC) 1107/2009 - Tritosulfuron
- Year:
- 2 018
- Bibliographic source:
- Draft Renewal Assessment Report under Regulation (EC) 1107/2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 850.1010 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
- Qualifier:
- according to guideline
- Guideline:
- other: EEC 79/831
- Principles of method if other than guideline:
- No deviations from the current guideline.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-amine
- EC Number:
- 610-962-9
- Cas Number:
- 5311-05-7
- Molecular formula:
- C5H5F3N4O
- IUPAC Name:
- 4-methoxy-6-(trifluoromethyl)-1,3,5-triazin-2-amine
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Details on test solutions:
- 5 test concentrations plus control, 4 replicates per concentration with 5 daphnid in each; assessment of immobility after 24 hours and at the end of the test after 48 hours. Control, 10, 18, 32, 56 and 100 mg/L (nominal). Glass vessels; test volume 50 mL,
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Waterflea (Daphnia magna STRAUS), neonates collected from in house culture, age at test initiation less than 24 hours; culture conditions in accordance with test conditions.
Study design
- Test type:
- static
- Water media type:
- other: synthetic water “M4” (Elendt medium)
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- total hardness 2.52 mmol/L
- Test temperature:
- 20 °C – 21 °C
- pH:
- 8.1 - 8.2
- Dissolved oxygen:
- 8.4 - 8.5 mg/L
- Conductivity:
- 655 μS/cm
- Details on test conditions:
- photoperiod 16 hours light : 8 hours dark; light intensity: < 1500 lux; no feeding, no ventilation
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
Any other information on results incl. tables
Tables are attached separately
Applicant's summary and conclusion
- Conclusions:
- Conclusion of the DAR (2001-2007): 48 h EC50 of > 100 mg a.s./L
- Executive summary:
Analytical measurements: Analytical verification of test substance concentration was conducted in each concentration at the beginning and at the end of the test. Measured values at test initiation ranged from 98.9% to 100.8% (average 99.9%) of nominal and from 97.8% to 99% (average 98.6%) of nominal at test termination, confirming the theoretical concentrations. Therefore, the following biological results are based on nominal concentrations.
In a 48 hours static acute toxicity study with Daphnia magna the EC50 (48 h) of BH 635-5 was determined to be > 100 mg/L, the EC0 (48 h) was 100 mg/L (nominal).
Biological results: No significant immobility of the daphnids was observed (one immobile daphnia at 32 mg/L after 48 hours). No other substance-related effects were observed.The study was effectively also conducted in compliance with the later version of the guideline, OECD TG 202 (2004), and fulfilled the validty criteria. Analytical measurements to confirm that the test concentrations remained at least 80% of nominal throughout the test period were done. We agree with the endpoint relevant for risk assessment, 48 h EC50 > 100 mg AMTT/L (nom), 48 h NOEC 100 mg AMTT/L (nom).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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