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EC number: 903-945-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on experimental data on each constituent, the reaction mass is considered as presenting no effect on the reproduction of daphnia magna with a 21d NOEC >= 10 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- 10 mg/L
Additional information
No data on long-term toxicity to aquatic invertebrates is available on the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA).
The following data are available on each constituent:
For CDFA, under semi-static conditions of 72 h-renewal, the effect on the reproductive output of Daphnia magna exposed to the test substance for 21 days was studied according to the OECD testing guideline 211 "Daphnia magna, Reproduction Test” and the GLP.
During the whole test period, the pH values of the control mediums and Test Media were between 6.9 and 7.5, and the Dissolved Oxygen (DO) values varied from 90% to 101% of the air saturation at the test temperature, the hardness values varied from 119 to 124 mg/L as CaCO3, and the temperature of the Test Media was maintained in the range of 20°C to 21°C. All animals in the control were alive and the mean number of live offspring produced per parent animal surviving at the end of the test was > 60. The coefficient of variation around the mean number of living offspring produced per parent animal in the control(s) was ≤25%. So the study met the acceptability criteria. Therefore the test was considered valid.
In order to confirm the stability of the test item in the test medium, concentrations of the test samples during the test were analyzed by GC-ECD.
The time to production of first brood was during the 7th and 8th 9th day. No aborted broods, male neonates or ephippia was observed. Throughout the test period, no dead adults were observed in the control and the treatments.
Compared with the reproduction of the controls, no significant differences were found in treatments (p<0.05). As a result, the NOEC (reproduction) is equal or greater than 10.0 mg/L (measured concentration 10.2 mg/L).
For TFA, the influence of 30% w/w Sodium trifluoroacetate aqueous solution to Daphnia magna was evaluated in a semi-static reproduction test, according to OECD guideline for testing of chemicals No. 211 and with GLP statement. This study encompassed 5 test concentrations (100, 32, 10, 3.2 and 1.0 mg test item/L) and one control with 10 replicates, each containing one Daphnia. The Daphnia were exposed for 21 days in a semi-static test.
The pH-values were in the range of 7.8 to 9.2; the dissolved oxygen concentrations were in the range of 8.0 to 10.1 mg/L and the water temperatures were in the range of 20 to 21°C. The light regime was 16 h light-8 h dark and the light intensity was 1000 -1100 lux. This test conditions were within the ranges requested by guideline OECD 211.
The concentrations of trifluoroacetate were measured in the duplicate test medium samples of 100 mg test item/L from all sampling date and were found to be sufficiently stable during the test medium renewal periods of 48 and 72 hours. Therefore, all reported results are related to nominal concentrations of the test item.
The biological results shows a 21-day NOEC for survival of adults and reproduction rate >= 100 mg test item/L (>= 25 mg trifluoroacetic acid/L). Besides, no particular signs of intoxication were observed at the test animals during the test.
Considering that the reaction mass of chlorodifluoroacetic acid (CDFA) and trifluoroacetic acid (TFA) is mainly composed of CDFA, the reaction mass is considered to have a NOEC for reproduction of daphnia > 10 mg/L.
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