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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1973

Materials and methods

Principles of method if other than guideline:
Six female rats exposed under static conditions to substantially saturated vapor for 8 hours and mortality recorded.
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Test material form:
liquid
Details on test material:
Name of test material: Trimethylolpropanepoly(oxypropylene)triamine
EC no.: 500-105-6
CAS no.: 39423-51-3
Physical state: clear colourless liquid

Test animals

Species:
rat
Strain:
Wistar
Sex:
female
Details on test animals or test system and environmental conditions:
TEST ANIMALS
- Weight at study initiation: 94.2

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
not specified
Vehicle:
other: no data
Details on inhalation exposure:
no data
Analytical verification of test atmosphere concentrations:
not specified
No. of animals per sex per dose:
6 females
Control animals:
not specified
Details on study design:
no data
Statistics:
no data

Results and discussion

Mortality:
No animals died
Clinical signs:
other:
Body weight:
Weight at initiation was 94.2; weight at termination was 157.2
Gross pathology:
Nothing remarkable

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
No mortality observed