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EC number: 211-711-2 | CAS number: 689-67-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: non GLP, Guideline study according to national standard protocol. No analytical monitoring.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: German standard DIN 38412, Part 15
- GLP compliance:
- no
Test material
- Reference substance name:
- 6,10-dimethylundeca-5,9-dien-2-one
- EC Number:
- 211-711-2
- EC Name:
- 6,10-dimethylundeca-5,9-dien-2-one
- Cas Number:
- 689-67-8
- Molecular formula:
- C13H22O
- IUPAC Name:
- 6,10-dimethylundeca-5,9-dien-2-one
- Details on test material:
- - Name of test material (as cited in study report): Geranylacetone
Test substance No.: 88/604
- Analytical purity: 92 %
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: Preparation of the test item: The test item was dissolved in acetone (1 g/100 ml) and was added to the test water, subsequently the fish were placed into the aquaria. Similarily to the highest amount of solvent used, 1 ml acetone/l was added to the control aquarium.
Test organisms
- Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- TEST ORGANISM
- Common name: Golden orfe
- Source: Fischzucht Paul Eggers, 2354 Hohenwestedt, Germany
- Length at study initiation (length definition, mean, range and SD): 6.0 cm (range 5.5 - 7.1 cm)
- Weight at study initiation (mean and range, SD): 1.8 g (range 1.2 - 2.8 g)
- Feeding during test. 1 day before and during exposure
- Housing: Duration of housing: about 1 month Mortality during the last 2 weeks of housing: 1.4 % , Medical treatment: twice with 0.05 mg/l malachite green chloride, once with 10 mg/l tetracycline hydrochloride.
ACCLIMATION
- Acclimation period: 3 days
- Health during acclimation (any mortality observed):no mortality observed
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 2.5 mmol/l
- Test temperature:
- 23 °C
- pH:
- 7.4 - 7.8
- Dissolved oxygen:
- 7.1 - 8.1 mg/l
- Nominal and measured concentrations:
- Nominal test concentrations: 1.0, 2.15, 4.64 and 10.0 mg/l. In addition, a control was tested in parallel.
- Details on test conditions:
- TEST SYSTEM
- Test vessel: glass aquaria (30 x 22 x 24 cm)
- Fill volume: 10 l
- Aeration: slight
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 1
- No. of vessels per control (replicates): 1
- No. of vessels per vehicle control (replicates): 1
- Biomass loading rate: 1.8 g fish/l test water
TEST MEDIUM / WATER PARAMETERS
- Ratio Na/K ions: 10 : 1
- Acid capacity: 0.8 mmol/l
- Ca/mg ratio: 4 : 1
- Intervals of water quality measurement: pH and oxygen content after 0, 24, 48, 72 and 96 h
OTHER TEST CONDITIONS
- Photoperiod: 16 : 8 hours day-night regime
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Mortality and symptoms of intoxication after 1, 4, 24, 48, 72 and 96 h
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 6.78 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- 96 h NOEC 2.2 mg/L (nominal) based on test material
96 h LC0 4.64 mg/L (nominal) based on test material
96 h LC100 10 mg/L (nominal) based on test material - Results with reference substance (positive control):
- The LC50 (48 h) of the positive control chloroacetamide was 23 mg/l, which corresponds to the normal sensitivity of the fish.
- Reported statistics and error estimates:
- The LC50 was statistically evaluated as the geometric mean of the LC0 (4.64 mg/l) and the LC100 (10 mg/l) nominal values.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.