Butanoic acid, 2-(ethoxymethylene)-4,4-difluoro-3-oxo-, ethyl ester

Guidance on Safe Use

First-aid measures

Inhalation: Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide

artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to mouth resuscitation. Get medical attention. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Ingestion: Wash out mouth with water. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed

person is conscious, give samll quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting

unless directed to do so by medical personnel. If vomitting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately.

Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband.

Skin contact

Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Continue to rinse for at least 10 minutes.

Get medical attention. Wash clothing before reuse. Clean shoes thoroughly before reuse.

Eye contact

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses.

Continue to rinse for at least 10 minutes. Get medical attention.

Fire-fighting measures

Suitable extinguishing media: In case of fire, use water spray (fog), foam, dry chemical or CO2. Never use water jet.

Unsuitable extinguishing media: None known

Hazards from the substance or mixture: In a fire or if heated, a pressure increase will occur and the container may burst. Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Hazardous combustion products: No specific data

Special protective equipment for fire-fighters

Fire-fighters should wear appropriate protective equipment and selfcontained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Accidental release measures

Personal precautions : No action shall be taken involving any personal risk or without suitable training. Keep unnecessary and unprotected personnel from

entering. Do not touch or walk through spilt material. Avoid breathing vapour or mist. Provide adequate ventilation. Put on appropriate personal protective equipment.

Environmental precautions

Avoid dispersal of spilt material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the

product has caused environmental pollution (sewers, waterways, soil or air).

Large spill :

Stop leak if without risk. Move containers from spill area. Prevent entry into sewers, water courses, basements or confined areas. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations. Dispose of via a licensed waste dispoasal contractor. Contaminated absorbent material may pose the same hazard as the spilt product.

Small spill :

Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container.  Dispose of via a licensed waste disposal contractor.

Handling and storage

Manufacture and use of this chemical intermediate takes place under strictly controlled conditions, as described in Art. 17/18 REACH. The substance is rigorously contained during manufacturing and use and appropriate risk management measures including PPE (i.g. during charging or sampling) are applied. Occupational exposure is reduced to a minimum and well controlled by measurements. A management system covering all general aspects of a chemical production is in place, especially cleaning and maintenance of plants and equipment. An authorisation scheme based on instructions covering the whole process ensures that only trained and authorised staff handles the substance.

Handling: Put on appropriate personal protective equipment. Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not

ingest.  Do not breathe vapour or mist. Do not get in eyes, on skin or clothing.  Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use.

Empty containers retain product residue and can be hazardous.

Storage:

Do not store above the following temperature: 25 °C (77 °F)

Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials and food and drink. Keep container tightly closed and sealed until ready for use. Containers

that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabelled containers. Use

appropriate containment to avoid environmental contamination.

Remarks: Reactive with bases, amines. Explosion hazard.

Protect from moisture. Air sensitive. Keep away from: oxygen

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure limit values: Not available

Recommended monitoring procedures:

If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to

determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective

equipment. Reference should be made to European Standard EN 689 for methods for the assessment of exposure by inhalation to

chemical agents and national guidance documents for methods for the determination of hazardous substances.

Risk management measures/Occupational exposure controls

Technical measures:  The substance shall be rigorously contained by technical means during its whole lifecycle including manufacture, purification, cleaning and maintenance of equipment, sampling, analysis, loading and unloading of equipment or vessels, waste disposal or purification and storage. Procedural and control technologies shall be used that minimise emission and any resulting exposure. In cases of accident and where waste is generated, procedural and/or control technologies shall be used to minimise emissions and the resulting exposure during purification or cleaning and maintenance procedures. Only properly trained and authorised personnel shall handle the substance. In case of cleaning and maintenance works, special procedures such as purging and

washing shall be applied before the system is opened and entered. Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapour or mist, use process enclosures, local exhaust to airborne contaminants below any recommended or statutory limits.

Personal protection measures: Use a properly fitted, air purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Recommended: Full mask with type ABEK filter. Wear breathing apparatus with seperate air supply (compressed air respirator, tube apparatus) at higher

concentrations.

Hand protection: Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical

products if  a risk assessment indicates this is necessary.  After contamination with product change the gloves immediately and

dispose of them according to relevant national and local regulations.

<1 hours (breakthrough time): Butyl rubber - IIR, Fluorinated rubber - FKM, polyvinyl chloride (PVC), Viton.

Eye protection: Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid

exposure to liquid splashes, mists, gases or dusts.

Recommended: Tightly fitting safety goggles.

Skin protection: Personal protective equipment for the body should be selected based on the task being performed and the risks involved and

should be approved by a specialist before handling this product.

Recommended: chemical resistant protective suit.

Hygiene measures: Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory

and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated

clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Environmental exposure controls: Emissions from ventilation or work process equipment should be checked to ensure they comply with the

requirements of environmental protection legislation. In some cases fume scrubbers, filters or engineering modifications to the process equipment will be

necessary to reduce emissions to acceptable levels.

Stability and reactivity

Reactivity: No specific test data related to reactivity available for this product or its ingredients.

Stability: The product is stable

Possibility of hazardous reactions: Under normal conditions of storage and use, hazardous reactions will not occur.

Conditions to avoid: No specific data

Incompatible materials: No specific data

Hazardous decomposition products: Under normal conditions of storage and use, hazardous decomposition products should not be produced.

Disposal considerations

Methods of disposal: Examine possibilities for re-utilisation. Product residues and uncleaned empty containers should be packaged, sealed,

labelled, and disposed of or recycled according to relevant national and local regulations. Where large quantities are concerned, consult the

supplier. When uncleaned empty containers are passed on, the recipient must be warned of any possible hazard that may be caused by residues.

For disposal within the EC, the appropriate code according to the European Waste List (EWL) should be used.

It is among the tasks of the polluter to assign the waste to waste codes specific to industrial sectors and processes according to the European

Waste List (EWL).

Hazardous waste: The classification of the product may meet the criteria for a hazardous waste.

The generation of waste should be avoided or minimised wherever possible. Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its containers must be disposed in a safe way. Care should be taken when handling emptied containers that have not been cleaned or rinsed out. Empty containers or liners may retain some product residues.

Avoid dispersal of split material and runoff and contact with soil, waterways, drains and sewers.