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Diss Factsheets
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EC number: 248-096-5 | CAS number: 26896-48-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 100.3 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 1.003 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 10.03 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 44 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 529.68 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 52.97 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 47 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Justification for PNEC soil derivation:
For the soil compartent, test with Earthworm (OECD 222) and nitrifying soil bacteria (OECD 216) are available: NOEC (earth worm, reprod., 56 d) = 59 mg/kg soil dw; EC10 (earth worm, reprod., 56 d) = 39 mg/kg soil dw. -- NOEC (nitrification inhib.; 28 d): 320 mg/kg soil dw; EC50 (nitrification inhib.; 28 d): 566 mg/kg soil dw. A test on toxicity to terrestrial plants is not available: The outcome of the CSA (implicating screening assessment based on equilibrium partitioning) indicates that available long-term toxicity tests on earthworm and soil microorganisms are appropriate to cover information requirements (waiving according to "column 2" in Annex X of REGULATION (EC) No 1907/2006, together with Guidance R.7c, chapter R.7.11.5). Further, in a reliable test according to OECD 201 (algae) neither any effects on growth rate nor biomass could be observed up to the highest concentration of 100 mg/L (concentration analytically verified). Thus, plants may not be the most sensitive trophic level, also with regard to soil. With regard to PNEC-soil derivation, REACH guidance R.10 states the following: “If only one terrestrial test result is available (earthworms or plants), the risk assessment should be performed both of this test result and on the basis of the outcome of the aquatic toxicity data to provide an indication of the risk. As a matter of precaution, the larger PECsoil/PNECsoil ratio determines which further actions should be taken in the framework of the further testing strategy. If additional soil test results are available the assessment factors given in Table R.10-10 should be applied”. As the additional nitrogen transformation test is available for which the NOEC is to be regarded as chronic, according to R.10 an AF of 50 is applied for two chronic NOEC/EC10 values from 2 trophic levels. Because EC10 (earthworm, reproduction, 56 d) is lower compared to the corresponding NOEC, AF 50 is applied to the EC10 of 39 mg/kg soil dw. The resulted PNEC soil would be 780 µg/kg dw.
However, the PNEC soil Screen is calculated using the equilibrium partitioning method (EPM) (derivation following procedures of TGD (R.10 and R.16): PNEC water (freshwater): 0.1 mg/L, Koc: 16.81 (EPA EPI Suite estimate, program PCKOC v1.66, IUCLID sect. 5.4.1), HLC: 0.0193 Pa*m³/mol (EPA EPI Suite estimate, program HENRY v3.10, IUCLID sect. 5.4.2)) resulted value is 47 µg/kg dw, which is more conservative than the PNEC soil calculated based on the soil test (780 µg/kg dw) , is used for the Exposure risk assessment calculations
Conclusion on classification
According to Regulation (EC) No 1272/2008, TCD Alcohol DM is not to be classified as hazardous for the aquatic environment as its acute toxicity is > 100.0 mg/L, the BCF is < 500, and the log Pow is < 4.0.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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