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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
other: Materials Studio
Title:
Unnamed
Year:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Annex V (Limit test)
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
405-370-0
EC Name:
-
Cas Number:
6334-25-4
Molecular formula:
Hill formula: C14 H28 N2 O6
IUPAC Name:
N,N,N',N'-tetrakis(2-hydroxyethyl)hexanediamide

Test animals

Species:
rat
Strain:
other: Crl: CDBr

Administration / exposure

Vehicle:
water

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
Male: 0 mg/kg bw; Number of animals: 6; Number of deaths: 0
Male: 5000 mg/kg bw; Number of animals: 6; Number of deaths: 0
Female: 0 mg/kg bw; Number of animals: 6; Number of deaths: 0
Female: 5000 mg/kg bw; Number of animals: 6; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: No deaths were observed. Diarrhoea was noted at 4 hours in the test group.
Gross pathology:
Effects on organs:
No treatment-related macroscopic findings were observed.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU