Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
review article or handbook
Title:
Fragrance material review on phenethyl alcohol
Author:
J.Scognamiglio, et al.
Year:
2011
Bibliographic source:
Food and chemical toxicology, doi: 10.1016/j.fct2011.10.028

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: refer to article
Deviations:
no
GLP compliance:
not specified
Test type:
fixed dose procedure

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Osborne-Mendel
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
unchanged (no vehicle)

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
>= 1 580 - <= 2 020 mg/kg bw
Based on:
test mat.
95% CL:
>= 1.4 - <= 1.7

Applicant's summary and conclusion