Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-862-8 | CAS number: 111-36-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
. General information:
Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.
· After inhalation: Supply fresh air. Consult doctor if symptoms persist.
· After skin contact:
Immediately remove any clothing soiled by the product.
Wash immediately with plenty of water and soap and rinse thoroughly.
· After eye contact:
Rinse opended eye for several minutes under running water.
· After swallowing: Rinse mouth and drink plenty of water.
Do not induce vomiting. Call a physician immediately.
Fire-fighting measures
· Suitable extinguishing agents: fire-extinguishing powder, CO2; only in case of big fire: water spray jet
· Unsuitable extinguishing agents for reasons of safety: water, foam.
· Special hazards caused by the material, its products of combustion or flue gases:
In case of fire, toxic incineration products can be released:
Nitrogen oxides (NOx)
Carbon oxides (COx)
Cyanic acid fumes (HCN)
· Protective equipment: Wear self-contained breathing apparatus.
· Additional information: Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.
Accidental release measures
· Personal safety precautions:
Wear respiratory protective equipment.
Ensure adequate ventilation.
Evacuate personnel to safe areas.
Remove all sources of ignition
Beware of vapours accumulating to form explosive concentrations.
Vapours can accumulate in low areas.
· Measures for environmental protection:
Prevent from spreading (e. g. by enclosing with a ring of chemical absorbent).
Do not allow substance to reach sewage system or water courses.
Inform authorities in case of contamination of water or sewage system.
· Measures for cleaning/collecting:
Soak up with an electrically protected vacuum cleaner or by wet-brushing.
Dispose of contaminated material as waste according to local regulations pertaining to the disposal of hazardous waste.
Provide adequate ventilation. Use respiratory protection in case of insufficient ventilation.
Handling and storage
Ensure "strictly controlled conditions" to avoid exposure.
· Handling:
· Precautions for safe handling:
It is preferable to handle the product in a closed system.
Ensure good exhaust ventilation at the workplace.
· Information about protection against explosion and fire:
Keep away from sources of ignition.
Protect against electrostatic charges.
· Storage:
· Requirements to be met by storerooms and containers:
Keep containers tightly sealed in a dry and well-ventilated place.
· Information about storage in a common storage facility:
Store in cool place.
· Further information about storage conditions:
Store container in a well ventilated position.
Protect from heat and hot surfaces.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2485
Shippingopen allclose all
Special provisions / remarks
- Special provisions:
- Tunnel restriction code: D/E
If transport in tanks: Tunnel restriction code: C/D/E
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 2485
Shipping information
- Proper shipping name and description:
- n-BUTYLISOCYANATE
- Chemical name:
- n-BUTYLISOCYANATE
- Language:
- English
- Labels:
- 6.1+3
Special provisions / remarks
- Remarks:
- Kemler Number: 663
Marine transport (UN RTDG/IMDG)
- UN number:
- 2485
Shipping information
- Proper shipping name and description:
- BUTYLISOCYANATE
- Chemical name:
- n-BUTYLISOCYANATE
- Labels:
- 6.1+3
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2485
Shipping information
- Proper shipping name and description:
- n-Butyl isocyanate
- Chemical name:
- n-Butyl isocyanate
- Labels:
- -
Special provisions / remarks
- Remarks:
- Passsenger Aircraft: Not permitted for transport
Cargo Aircraft: Not permitted for transport
SpecialProvisionsopen allclose all
Exposure controls / personal protection
· Additional information about design of technical systems: ensure "strictly controlled conditions" to avoid any exposure
· Components with critical values that require monitoring at the workplace:
For the substance is no critical value known that have to be monitored at the workplace.
· Additional information: Information valid at the time of review of safety data sheet.
· Personal protective equipment
· General protective and hygienic measures:
Use skin cream for skin protection.
Avoid contact with the eyes and the skin.
Do not inhale gases/fumes/aerosols.
Immediately remove any soiled and impregnated garments.
· Respiratory protection:
For short-term or low-level exposure use respiratory protection of type ABEK (EN 14387).
For longer or heavier exposure use self-contained respiratory equipment.
· Protection of hands:
Chemical protective gloves according to DIN EN 374 with CE-labelling.
Check the condition of protective gloves after each use for any damages like holes, cuts or tears.
After use of gloves apply skin-cleaning agents and skin cosmetics.
· Material of gloves: Selection of the glove material on consideration of the penetrating times, rates of diffusion and the degradation.
· Gloves made of the following materials are not suitable: Leather gloves
· Eye protection:
Tightly fitting safety goggles to DIN EN 166.
· Body protection:
Protective clothing.
Stability and reactivity
· Conditions to be avoided:
Heat, flames, and sparks. Extremes of temperature and direct sunlight.
· Minimum shelf life:
24 months from production date.
· Possibility of hazardous reactions:
Reacts with water heavily under development of HCN
Polymeriasation if heated
· Incompatible materials:
Water
Alcohols
Amines
Acids
Oxidizing agents
· Hazardous decomposition products: HCN
Disposal considerations
· Product:
· Recommendation:
Product must be disposed of according to local regulations pertaining to the disposal of hazardous waste.
Incineration at a licensed professional waste disposal facility is recommended.
· Contaminated packaging:
· Recommendation:
Packagings are to be disposed of in the same manner as the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.