Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
key study
Study period:
3 October 1996 to 5 May 1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study in accordance with internationally recognised guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1997
Report Date:
1997

Materials and methods

Test guideline
Guideline:
other: OECD Guideline for Testing of Chemicals: Delayed Neurotoxicity of Organophosphorus Substances.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Applicant's summary and conclusion

Conclusions:
The present study has clearly indicated that AOK STAB PEP-36 applied to hens orally by gavage, daily for 28 days, at a limit-dose of 1000 mg/kg showed no effects of a neurotoxic potency when compared to the positive control substance TOTP.