Registration Dossier
Registration Dossier
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EC number: 410-290-4 | CAS number: 80693-00-1 ADK STAB PEP-36
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 3 October 1996 to 5 May 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study in accordance with internationally recognised guidelines
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Guideline:
- other: OECD Guideline for Testing of Chemicals: Delayed Neurotoxicity of Organophosphorus Substances.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3,9-bis(2,6-di-tert-butyl-4-methylphenoxy)-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane
- EC Number:
- 410-290-4
- EC Name:
- 3,9-bis(2,6-di-tert-butyl-4-methylphenoxy)-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane
- Cas Number:
- 80693-00-1
- Molecular formula:
- Hill formula: C35H54O6P2 CAS formula: C35H54O6P2
- IUPAC Name:
- 3,9-bis(2,6-di-tert-butyl-4-methylphenoxy)-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- The present study has clearly indicated that AOK STAB PEP-36 applied to hens orally by gavage, daily for 28 days, at a limit-dose of 1000 mg/kg showed no effects of a neurotoxic potency when compared to the positive control substance TOTP.
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