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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EPA OPPTS 850.1010 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Analytical monitoring:
no
Vehicle:
no
Details on test solutions:
- No vehicle used.
- Stock solutions (1000 and 10mg/L) and the test solutions were homogenously dispersed at the beginning of the test.
- After 24hours pink sediment was observed in the stock solutions.
- Dissolved concentrations determined at 0.01 to 1 mg/L
Test organisms (species):
Daphnia magna
Details on test organisms:
-48h before test the parental daphnids were maintained in 100% dilution water under test conditions.
- During production of neonates the daphnids were not fed
- Otherwise 5x weekly ad libitum feeding
Test type:
static
Water media type:
freshwater
Total exposure duration:
96 h
Post exposure observation period:
- Immobilisation of daphnids onserved - see results table
Test temperature:
20 +/- 2 degree celcius
pH:
adjusted to 6.95 with HCL
Salinity:
N/A
Nominal and measured concentrations:
Nominal; 0.01, 0.1, 1.0, 10, 100, 1000 mg/L
Reference substance (positive control):
yes
Remarks:
potassium dichromate
Duration:
24 h
Dose descriptor:
EC10
Effect conc.:
359 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
702 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Duration:
24 h
Dose descriptor:
EC100
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC10
Effect conc.:
0.22 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
2.4 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
dissolved
Basis for effect:
mobility
Results with reference substance (positive control):
EC50 at 2.3mg/L after 24hr was within the prescribed concentration range of 1.0 to 2.5 mg/L.
Validity criteria fulfilled:
yes
Conclusions:
EC50 @ 24h = 702mg/L
EC50 @ 48h = 2.4 mg/L
Executive summary:

The EC50 value after 48hours was found to be 2.4 mg/L under the conditions of this study.

Description of key information

The EC50 value after 48hours was found to be 2.4 mg/L under the conditions of this study.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Dose descriptor:
EC50
Effect concentration:
2.4 mg/L

Additional information