Piperonal

Oxidising properties

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

oxidising solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied

Justification for type of information:

JUSTIFICATION FOR DATA WAIVING
In accordance with column 2 of REACh Annex VII, the study does not need to be conducted if the substance is incapable of reacting exothermically with combustible materials, for example on the basis of the chemical structure.
According to Regulation (EC) N°1272/2008 (CLP) criteria (Annex I §2.13.4./2.14.4., or as listed in the ECHA endpoint specific guidance on information requirements (R.7a, v6.0, July 2017, §R.7.1.13)), the substance contains oxygen atoms, but this element is chemically bonded only to carbon (especially not bonded to nitrogen or other oxygen).
Then oxidising properties are unlikely, and the classification procedure shall not apply, no further testing is required.

Reference 2

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

16 April 2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

GLP compliant study in compliance with international recognized guidelines.

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Version / remarks:

2008

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

UN Manual of Tests and Criteria: Test O.1 (Test for oxidizing solids)

Deviations:

no

GLP compliance:

yes

Contact with:

powdered cellulose

Duration of test (contact time):

509 s

Sample tested:

test mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

505 s

Remarks on result:

other: test substance-cellulose 4:1 mixture; mean burning time 494 ± 8.5 seconds

Sample tested:

test mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

525 s

Remarks on result:

other: test substance-cellulose 1:1 mixture; mean burning time 509 ± 12.5 seconds

Sample tested:

reference mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

155 s

Remarks on result:

other: potassium bromate-cellulose 3:7; mean burning time 149 ± 5.2 seconds

Interpretation of results:

study cannot be used for classification

Conclusions:

The mean burning times of the 4:1 and 1:1 sample to cellulose mixtures were significantly higher than the mean burning time of the standard 3:7 mixture of potassium bromate to cellulose.

Executive summary:

Following EU Method A.17 mixtures of Heliotropine (piperonal) and cellulose were prepared in the oxidiser to cellulose ratios of 4:1 and 1:1, by mass. The mixtures were ignited and the burning time was compared to the reference sample of a potassium bromate to cellulose mixture 3:7, by mass. The mean burning times of the 4:1 and 1:1 sample to cellulose mixtures were significantly higher than the mean burning time of the standard. Heliotropine (piperonal) does not possess oxidizing properties.

Description of key information

In accordance with column 2 of REACh Annex VII, the study on oxidising properties (required in section 7.13) does not need to be conducted if the substance is incapable of reacting exothermically with combustible materials, for example on the basis of the chemical structure.

This is supported by a negative A17 study, but the method is not suitable with regard to CLP criteria.

Key value for chemical safety assessment

Oxidising properties:

no

Additional information

Following EU Method A.17 mixtures of Heliotropine (piperonal) and cellulose were prepared in the oxidiser to cellulose ratios of 4:1 and 1:1, by mass. The mixtures were ignited and the burning time was compared to the reference sample of a potassium bromate to cellulose mixture 3:7, by mass. The mean burning times of the 4:1 and 1:1 sample-to-cellulose mixtures were significantly higher than the mean burning time of the standard. Heliotropine (piperonal) does not possess oxidizing properties.

Justification for classification or non-classification

The chemical structure substance meets the exemption criteria, according to Regulation (EC) No 1272/2008, Annex I section 2.14.

This is sufficient for (non-)classification purpose.

In the A.17 study that was used for DSD criteria, the reference mixtures differ from the O1 method used for classification according to CLP, therefore the conclusion cannot be extrapolated. However, the negative result supports the lack of potential for the substance.