Registration Dossier
Registration Dossier
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EC number: 616-149-5 | CAS number: 74860-00-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-({9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}methyl)-2,3-dihydro-1H-isoindole-1,3-dione
- EC Number:
- 616-149-5
- Cas Number:
- 74860-00-7
- Molecular formula:
- C23 H16 N2 O2
- IUPAC Name:
- 2-({9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}methyl)-2,3-dihydro-1H-isoindole-1,3-dione
Constituent 1
Study design
- Inoculum or test system:
- activated sludge, domestic, adapted
- Duration of test (contact time):
- 28 d
Results and discussion
% Degradation
- Parameter:
- other: ThOD
- Value:
- >= 12 - <= 16
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- After correction of the mean biochemical oxygen demand of the inoculum contrals at the end of the 28-day exposure period degradation rates of
12 % and 16 % were found based on ThODNH4.
If the calculation of biodegradation is based on ThO~03, percentage bio degradation reached 10 % and 14 % after 28 days of incubation.
The percentage biodegradation did not exceed 60 % within the 10-day window. The test substance can therefore not considered to be ready
biodegradable.
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