Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: No experimental details, but published in peer-reviewed publication.

Data source

Reference
Reference Type:
grey literature
Title:
Further Toxicologic Studies with Commercial and Candidate Flame Retardant Chemicals. Part II.
Author:
A.T. Eldefrawi et al
Year:
1977
Bibliographic source:
Bulletin of Environmental Comtamination and Toxicology, Vol.17, No.6.

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No information available other than report of LD50 (rat) as part of a wider investigation.
GLP compliance:
no
Test type:
other: LD50

Test material

Constituent 1
Reference substance name:
Fyrol CEF
IUPAC Name:
Fyrol CEF
Details on test material:
Not available

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified
Details on test animals or test system and environmental conditions:
Not available

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Details on oral exposure:
Not available
Doses:
Not available
No. of animals per sex per dose:
Not available
Control animals:
not specified
Details on study design:
Not available
Statistics:
Not available

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 230 mg/kg bw
Based on:
test mat.
Mortality:
No data
Clinical signs:
No data
Body weight:
No data
Gross pathology:
No data

Any other information on results incl. tables

No further data available.

Applicant's summary and conclusion

Interpretation of results:
Toxicity Category IV
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Rat oral LD50, 1230 mg/kg bw