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EC number: 241-155-6 | CAS number: 17090-93-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 022
- Report date:
- 2022
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
Test material
- Reference substance name:
- sodium 2-amino-3-carboxypropanoate
- Cas Number:
- 323194-76-9
- Molecular formula:
- C4H7NO4.xNa
- IUPAC Name:
- sodium 2-amino-3-carboxypropanoate
- Test material form:
- solid: particulate/powder
- Details on test material:
- Name: L-aspartic acid, sodium salt monohydrate 1
Batch/Lot number: Z201125/ VG29848563
CAS number: 323194-76-9
Anhydrous substance name: L-aspartic acid, sodium salt, CAS: 17090-93-6
Appearance: Solid, white, crystalline powder
Purity: 98%
Expiry date: 24 November 2022
Storage conditions: Room temperature (15-25 ºC), protected from humidity (tight closed
container)
Constituent 1
- Specific details on test material used for the study:
- 2.1. Test item:
Test item: L-Aspartic Acid Monosodium Salt Monohydrate
Number CAS: monohydrate: 323194-76-9 (anhydrous: 17090-93-6)
Purity: 99.9%
Appearance: solid, crystalline powder, white
Lot number: VG29848563 Z201125
Manufacturing date: 25.11.2020
Expiry date: 24.11.2022
Producer: Chemos GmbH Co.KG
Sponsor Global Life Sciences Solutions Austria GmbH & Co KG
Storage Conditions: 15 – 30°C
Sample code : 35 /22
Results and discussion
Vapour pressureopen allclose all
- Key result
- Test no.:
- #2
- Temp.:
- ca. 25 °C
- Vapour pressure:
- ca. 0 Pa
- Key result
- Test no.:
- #1
- Temp.:
- ca. 20 °C
- Vapour pressure:
- ca. 0 Pa
Applicant's summary and conclusion
- Conclusions:
- Vapour pressure at 20 C:=1.1*10-5 Pa
Vapour pressure at 205C:=3.65*10-5 Pa - Executive summary:
Vapour pressure at 20 C:=1.1*10-5 Pa
Vapour pressure at 205C:=3.65*10-5 PaThe study of the vapour pressure determination using effusion method is performed in accordance with an elaborated Standard Operating Procedure SPO/BC/13/b (3rd ed.). This procedure complies with the method EC A4.
The described method is used for liquid and solid substances. Recommended by guideline range for this effusion method using Knudsen cell is 10 to 10-10 1 Pa, however apparatus employed in the test with Knudsen cell possessing 0.336 mm or 0.1mm orifice diameters allows to determine vapour pressure in the range of 10-15 Pa – 500 Pa.
The method is based on the estimation of the mass of test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions.
The vapour pressure was calculated by applying the Hertz-Knudsen relation with Clausing correction factor f that depends on parameters of the apparatus.
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