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Diss Factsheets
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EC number: 203-950-6 | CAS number: 112-24-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Based on the results from the Acute Exposure Oral Toxicity in rats, the acute oral LD50 for males, females and combined sexes was determined to be 1861.9 (1383.5 - 2505.7) mg/kg, 1591.4 (1283.5 - 1973.3) mg/kg and 1716.2 (1446.5 - 2036.1) mg/kg, respectively.
No valid data available for acute inhalation toxicity that can be used for classification and labelling; the studies performed were intended to examine the toxicity of the vapour under realistic exposure conditions.
Based on the observations made in the Acute Exposure Dermal Toxicity Study in rabbits, the acute dermal LD50 in males and combined sexes for 6933-6-20 was determined to be 1720.0 (1082.9-2732.0) mg/kg and 1465.4 (1074.6-1998.3) mg/kg, respectively. The data generated for the acute dermal LD50 in females did not lend itself to the statistical method employed.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 716 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 1 465 mg/kg bw
Additional information
Three old inhalation studies were available in which rats had been exposed to the vapour of TETA generated at room T (21 or 25 degrees C) or at 100 degrees C for a single period of 7 to 8 hours. No mortality occurred. In none of the studies the concentration had been measured. It was, however, noted that in one of the studies no substance loss but an increase in substance weight was recorded. This is an indication that the test substance is hygroscopic and only a marginal fraction of the test substance might have been volatile. From a toxicologists point of view it is therefore doubtful if the animals were exposed to the test substance by inhalation and which concentration the generated vapour was of.
Justification for classification or non-classification
Based on the acute oral and dermal study classification is needed in GHS Category 4. The acute inhalation studies performed could not be used for classification.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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