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Diss Factsheets
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EC number: 617-298-9 | CAS number: 82097-50-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
Two long-term toxicity studies on birds are available and included as supporting information. More details are provided in additional information.
Key value for chemical safety assessment
Additional information
Studies required in Annex VII and some other studies required for higher tonnage are available. All the studies available have been included in the dossier for this endpoint. There are two long-term studies available for this endpoint. Both studies were performed without the use of standard guidelines and under GLP. Males and females of Anas platyrhynchos (26 weeks old at test initiation) were offered a test diet containing 100, 500 and 1000 mg/kg diet for 19 weeks. A similar-sized control group was given an untreated diet only. Samples collected during the test to verify test substance concentrations for the 100, 500 and 1000 ppm diets were found to be 133 to 141%, 86 to 128%, and 85 to 115 % of nominal concentrations, respectively. There were no mortalities or signs of toxicity observed in any of the parameters tested, in adult or F1 generation birds, that were considered to be treatment-related. The 19-wk NOEC was determined to be 1000 mg/kg diet based on nominal concentrations (Fletcher 1985). Males and females of Colinus virginianus (27 weeks old at test initiation) were offered a test diet containing 100, 500 and 1000 mg/kg diet for 19 weeks. A similar-sized control group was given an untreated diet only. Samples collected during the test to verify test substance concentrations for the 100, 500 and 1000 ppm diets were found to be 133 to 141%, 86 to 128%, and 85 to 115 % of nominal concentrations, respectively. There were no mortalities or signs of toxicity observed in any of the parameters tested, in adult or F1 generation birds, that were considered to be treatment-related. The 19-wk NOEC was determined to be 1000 mg/kg diet based on nominal concentrations (Fletcher 1986).
There are six short-term studies available for this endpoint. These studies are not summarized as an endpoint study entry but are briefly discussed here. Three of the studies were carried out on bobwhite quail and the other three studies were on mallard duck. The LD(/C)50 for bobwhite quail was determined to be >2000 and > 2150 mg/kg bw, and > 5000 mg/kg diet in the studies performed by Hubbard&Beavers (2013a), Fletcher (1984a) and Fletcher (1984b), respectively. The LD(/C)50 for mallard duck was determined to be >2000 and > 2150 mg/kg bw, and > 5000 mg/kg diet in the studies performed by Hubbard&Beavers (2013b), Fletcher (1984c) and Fletcher (1984d), respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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