Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-472-2 | CAS number: 83-38-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38 412-1,11 (1982)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,6-dichlorobenzaldehyde
- EC Number:
- 201-472-2
- EC Name:
- 2,6-dichlorobenzaldehyde
- Cas Number:
- 83-38-5
- Molecular formula:
- C7H4Cl2O
- IUPAC Name:
- 2,6-dichlorobenzaldehyde
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
Test conditions
- Nominal and measured concentrations:
- 2.9-21.5 mg/l
- Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- >= 8.2 - <= 11.57 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other:
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- 2,6-Dichlorobenzaldehyde is toxic to Daphnia Magna Strauss.
- Executive summary:
The observation period was 24 hours. Current test methods require observation over 48 hours. In the case of repetition according to the new test regulations, the result of the EC50 could therefore be a few mg / l lower. With a possible influence on the result, the almost tenfold excess of the test sample weight for the production of the saturated solution must also be assessed. Since 2,6-dichlorobenzaldehyde as a chemical is usually of high purity, the deviation of the result due to this approach is to be assessed as minor. The result of the EC50 of this test is at the upper end of the evaluation range from 1 to 10 mg / l for the statement "toxic to the test organisms". Therefore, even if carried out according to the current method and with only a slight excess in the preparation of the saturated solution, an evaluation as "very toxic" would not be expected. The EC50 would have to be lower by a factor of about 8 to 10 (<= 1 mg / l). On the other hand, a more favorable evaluation when the test is repeated is also extremely unlikely because of the longer test duration. Other differences between the earlier methods and today's methods, such as changes in the mineral content of the dilution water, have no significant influence on the test result.
The validity of the present test result is graded down due to the deviations from the current procedure presented here and due to the small volume of the archived laboratory records, on the other hand, taking into account the discussion in the previous paragraph and the general status of the presentation in the year the test was carried out, it is still sufficient for general risk assessments judged.
Für das Ergebnis der Toxizitätsprüfung von 2,6-Dichlorbenzaldehyd im Daphnien-Kurzzeittest wurde die folgende Bewertung abgegeben:
2,6-Dichlorbenzaldehyd ist giftig gegenüber Daphnia magna STRAUSS; Wasserfloh. Die EC50 liegt im Bewertungsbereich >l mg/l bis 10 mg/l.
The following rating was given for the result of the toxicity test of 2,6-dichlorobenzaldehyde in the daphnia short-term test: 2,6-dichlorobenzaldehyde is toxic to Daphnia magna STRAUSS; Water flea.
The EC50 is in the evaluation range > 1 mg / l to 10 mg / l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.