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EC number: 603-520-1 | CAS number: 131807-57-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Phototransformation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- phototransformation in soil
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EPA Guideline Subdivision N 161-3 (Photodegradation Studies on Soil)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: EU Annex II Proposed Guideline 7.1.1.1.2
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Substance name: [4-Phenoxyphenyl-14C]DPX-JE874 ([POP-14C]DPX-JE874)
Lot #: 2675-268
Specific activity: 59.6 µCi/mg
Radiochemical purity: >91%
Substance name: [Phenylamino-14C]DPX-JE874 ([PA-14C]DPX-JE874)
Lot #: 3048-238
Specific activity: 58.5 µCi/mg
Radiochemical purity: >98% - Radiolabelling:
- yes
- Analytical monitoring:
- yes
- Analytical method:
- gas chromatography
- high-performance liquid chromatography
- mass spectrometry
- Details on soil:
- [POP-14C]test substance:
Soil classification: Sandy Loam
pH: 6.9
% Sand: 64.0
% Silt: 24.0
% Clay: 12.0
% Organic matter: 1.4
CEC (meq/100 g): 9.9
Bulk density (lb/cu ft): 76
Field capacity (% soil moisture at 1/3 bar): 10.8
[PA-14C]test substance:
Soil classification: Sandy Loam
pH: 7.2
% Sand: 53.2
% Silt: 36.0
% Clay: 10.8
% Organic matter: 1.4
CEC (meq/100 g): 9.2
Bulk density (lb/cu ft): 83
Field capacity (% soil moisture at 1/3 bar): 12.3 - Light source:
- Xenon lamp
- Light spectrum: wavelength in nm:
- 225 - 229
- Relative light intensity:
- 10 447 - 12 316
- Duration:
- 15 d
- Temp.:
- 24 °C
- Initial conc. measured:
- 200 g/ha d.w.
- Dark controls:
- yes
- DT50:
- > 30 d
- Test condition:
- non-irradiated
- Key result
- DT50:
- 4.1 d
- Test condition:
- irradiated sample at 24°C
- Remarks on result:
- other: 11.5 days correlated to natural sunlight
- Transformation products:
- yes
- Remarks:
- JS940, KF015, H3310, MN468, and MN467
- Validity criteria fulfilled:
- yes
- Conclusions:
- Under the conditions of this study, the test substance degraded with a calculated average first-order half-life of 4.1 days (11.5 days correlated to natural sunlight) while under nonirradiated conditions the average half-life was greater than 30 days.
- Executive summary:
The study was conducted following US EPA guideline 161-3. The study investigated the effect of simulated sunlight on the route and the rate of degradation of test substance on soil thin layers. Solutions of [4-phenoxyphenyl-14C]test substance or [phenylamino-14C]test substance were applied to thin layers of Speyer sandy loam soil at a rate equivalent to 200 g ai/ha. Soil samples of each label were continuously irradiated under xenon arc lamps inside a Suntest® exposure unit for a period of 15 days (approximately 360 exposure hours, equivalent to approximately 42 days of natural summer sunlight in Wilmington, Delaware U.S.A.). Soil samples, prepared in the same manner, were shielded from light to serve as dark controls. The temperature of the test samples was maintained at approximately 24°C throughout the study.
Degradation of the test substance on layers of soil irradiated with simulated sunlight was substantially faster than degradation of identical samples under non-irradiated conditions. Under the conditions of this study, the test substance degraded with a calculated average first-order half-life of 4.1 days (11.5 days correlated to natural sunlight) while under nonirradiated conditions the average half-life was greater than 30 days.
Substantial mineralization to 14CO2 occurred in both labels [POP (10%), PA (30%)] after 15 days of continuous irradiation. The major extractable degradation products were identified as JS940, KF015, H3310, MN468, and MN467. JS940, KF015, and H3310 each retain the phenoxyphenyl ring system. MN467 and MN468 are nitro analogs of the test substance and were found in irradiated and non-irradiated samples.
The substantial difference in degradation rate between the irradiated and non-irradiated samples indicates photolytic processes on soil surfaces could enhance the overall rate of degradation of test substance in the environment.
Reference
Description of key information
Study Type | Study Details | Value | Guideline | Reliability |
Phototransformation in soil | Applied on thin layers of Speyer sandy loam soil | DT50 = 4.1 days | EPA 161-3 | 1 |
Key value for chemical safety assessment
- Half-life in soil:
- 4.1 d
Additional information
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