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EC number: 401-610-3 | CAS number: 122012-52-6 GENIPLEX A
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- until 1986-11-13
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- Study was attempted, but substance decomposes.
- GLP compliance:
- no
- Other quality assurance:
- other: self-stated
- Type of method:
- column elution method
- Water solubility:
- ca. 0.1 g/L
- Incubation duration:
- 2 h
- Temp.:
- 20 °C
- Remarks on result:
- other: A standard test was performed to provide an apparent solubility of the test item in water and was estimated to be approximately 10exp(-2) g/l at room temperature (approximately 20°C).
- Conclusions:
- 0.009 g of the test material did not dissolve in 100 ml of water but formed a flocculate. However, on making up to 1000 ml and leaving for 24 hours the flocculate appeared to disperse. The apparent solubility was therefore described as ~ 10exp(-2)
- Executive summary:
The test item was found to be unstable in water at 25 °C over a time period of two hours. Decomposition precludes measurement of the water solubility of essentially pure material according to OECD test guidelines. However, a standard test was performed to provide an apparent solubility and this was estimated to be approximately 10-2g/l at room temperature (approximately 20 °C). The physical process studied appeared to be one of dispersion rather than dissolution.
Reference
pH values of the prepared mixtures are given in Table 1 and results of microanalysis on the isolated solids in Table 2.
Table 1 pH of test item – water mixtures
Mixture |
Initial pH |
pH after 2 h |
A |
8.59 |
8 |
B |
8.57 |
8 |
C |
8.57 |
8 |
The pH of distilled water prior to use was 6.1.
Table 2 Microanalysis of isolated solids
Sample |
Empirical Formula |
C2H6N4O2Zn |
||
|
|
Analysis |
||
|
|
% C |
% H |
% N |
|
Theory |
13.07 |
3.29 |
30.64 |
Test item |
Found |
12.46 |
2.62 |
29.91 |
A |
Found |
4.21 |
1.45 |
4.44 |
B |
Found |
4.16 |
1.43 |
4.24 |
C |
Found |
4.31 |
1.48 |
4.60 |
Thermal instability of the test item at 50 °C over a 24 h time period has been reported elsewhere. However, the level of decomposition was much less than indicated here for decomposition of the test item in water. Therefore, it was concluded that the drying of isolated solids at 40 °C for approximately 2 h prior to microanalysis did not significantly contribute to the overall finding of gross decomposition. The pH measurements of water mixtures of the test item were consistent with rapid decomposition accompanied by release of ammonia.
The test item was therefore found to be unstable in water at 25 °C over a time period of 2 h.
Description of key information
Water solubility, OECD 105: The test item was found to be unstable in water at 25 °C over a time period of two hours, solubility was estimated to be approximately 10-2g/l
Key value for chemical safety assessment
- Water solubility:
- 0.1 g/L
- at the temperature of:
- 20 °C
Additional information
The test item was found to be unstable in water at 25 °C over a time period of two hours. Decomposition precludes measurement of the water solubility of essentially pure material according to OECD test guidelines. However, a standard test was performed to provide an apparent solubility and this was estimated to be approximately 10-2g/l at room temperature (approximately 20 °C). The physical process studied appeared to be one of dispersion rather than dissolution.
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