Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 404-170-0 | CAS number: 70750-63-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The toxicokinetic assessment was derived from available physiochemical and toxicity data, not based on actual experimental examinations..
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
- Objective of study:
- toxicokinetics
Test guideline
- Qualifier:
- no guideline followed
- Deviations:
- not applicable
- Principles of method if other than guideline:
- Toxicokinetic assessment was performed based on physicochemical properties and available toxicity data
- GLP compliance:
- not specified
Test material
- Details on test material:
- - Physical state: blue powder
Constituent 1
- Radiolabelling:
- no
Test animals
- Species:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
- Strain:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
- Vehicle:
- unchanged (no vehicle)
- Duration and frequency of treatment / exposure:
- Not Applicable
Doses / concentrations
- Remarks:
- Doses / Concentrations:
Not Applicable
- No. of animals per sex per dose / concentration:
- Not Applicable
- Control animals:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
- Positive control reference chemical:
- Not applicable
- Details on study design:
- Not applicable
- Details on dosing and sampling:
- Not applicable
- Statistics:
- Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
Results and discussion
- Preliminary studies:
- Not Applicable
Toxicokinetic / pharmacokinetic studies
- Details on absorption:
- Not Applicable
- Details on distribution in tissues:
- Not Applicable
Transfer into organs
- Transfer type:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
- Observation:
- not determined
- Details on excretion:
- Not Applicable
Toxicokinetic parameters
- Toxicokinetic parameters:
- other: Prediction toxicokinetic behavior based on physicochemical properties and available toxicity data.
Metabolite characterisation studies
- Metabolites identified:
- not measured
- Details on metabolites:
- Not Applicable
Any other information on results incl. tables
The information used for toxicokinetic assessment was listed below:
Physicochemical Property And Toxicity Test Data Of 1779u
Property |
Value |
Molecular Formula |
(C32H15CuN8).(O3S)x(C38H80N)x, x= 1.2~1.4 |
Physical |
Blue powder |
Particle Size |
46.6% passed through a 38mm sieve |
Melting Point |
> 250oC |
Specific Gravity |
1.26 g/cm3 |
Water Solubility |
< 0.24 mg/L |
Acute Oral Toxicity, Rat |
> 5000 mg/kg |
Acute Dermal Toxicity, Rat |
> 2000 mg/kg |
Skin Irritation, Rabbit |
Not classified |
Eye Irritation, Rabbit |
Not classified |
Skin Sensitization, Guinea-pig |
Not classified |
Sub-acute Toxicity, Rat |
NOEL 1000 mg/kg/day |
Inhibition of Activated Sludge Respiration |
LC50 > 1000 mg/L |
Algal Toxicity |
NOEC > 0.24 mg/L |
There was evidence of systemic toxicity in the repeat dose toxicity study at 1000 mg/kg/day, with effects seen in the spleen, stomach and liver indicating that absorption, possible metabolism and excretion process were involved.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): other: predicted no bioaccumulation.
Based on the representative chemical structure and available physicochemical property and toxicity data, a prediction of toxicokinetic behavior was created, and absorption, distribution to distance organs, possible metabolism and excretion process were involved. - Executive summary:
The test material has a molecular weight range from 1332.4 (x=1.2) to 1458.6 (x=1.4). It is poorly water soluble (< 0.24 mg/L). Based on the representative chemical structure and available physicochemical property and toxicity data, a prediction of toxicokinetic behavior was created
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Vi har mycket webbmaterial på ditt språk, men en del av den här sidan finns bara på engelska. Mer om vår flerspråkighetspolicy finns.
Välkommen till Echas webbplats. Alla funktioner på den här webbplatsen fungerar inte med Internet Explorer 7 (eller tidigare versioner). Det är därför bäst att du uppgraderar till en nyare version.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Läs mer om hur vi använder kakor.