Registration Dossier
Registration Dossier
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EC number: 238-173-1 | CAS number: 14281-83-5
Endpoint summary
Administrative data
Description of key information
According to Regulation (EC) No. 1907/2006 (REACH) Annex VII, section 9.2.1.1, column 2, the study does not need to be conducted because the substance is inorganic.
Additional information
The target substance bis(glycinato-N,O)zinc is constituted of two main components, glycine, and zinc. It is considered to dissociate in aqueous solutions thus, in biodegradation screening tests the single components are assessed. Zinc is inorganic and thus testing for biodegradation is technically not feasible. The other component, glycine, is a ubiquitously occurring amino acid which is known to be readily metabolised by virtually every organism (common textbooks of biochemistry). Furthermore, it was shown to be readily biodegraded by activated sludge (Carlson & Polkowski 1962; Malaney, 1969; Placak & Ruchhoft, 1947; Bernheim et al., 1935). Based on this information, bis(glycinato-N,O)zinc is not considered to be less biodegradable than its main constituent.
Carlson D.A., June 1965, UTILIZATION OF FREE AND COMBINED AMINO ACIDS BY ACTIVATED SLUDGE
Dale A. Carlson and L. B. Polkowski, Journal (Water Pollution Control Federation), Vol. 34, No. 8 (Aug., 1962), pp. 816-829
Malaney GW and Gerhold RM, Warburg Tests, Vol. 41. No.2, Part 2, 1969
O. R. Placak and C. C. Ruchhoft, Sewage Works Journal, Vol. 19, No. 3 (May, 1947), pp. 423-440
Bernheim F, Bernheim MLC and Webster MD, OXIDATION OF CERTAIN AMINO ACIDS BY “RESTING” BACILLUS PROTEUS. J. Biol. Chem., 110, 165-172. 1935
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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