Registration Dossier
Registration Dossier
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EC number: 900-986-0 | CAS number: -
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Type of information:
- other: bibliography
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- Calendula officinalis mother tincture is a UVCB and natural complex substance, and is assesed through constituents approach taking into account one the main constituent : ethanol present at 55%. The second main constituent is water.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.5 (Degradation: Biochemical Oxygen Demand)
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- wastewater from domestic sewage
- Duration of test (contact time):
- > 5 - <= 20 d
- Details on study design:
- Three concentrations tested (3, 7 and 10 mg/l) with at least two in duplicate. Tested concentrations gave a BOD of 3 to 30mg/l. Dissolved oxygen measured periodically (5 times in 20 days).
- Parameter:
- other: BOD protocol
- Value:
- 74
- Sampling time:
- 5 d
- Remarks on result:
- other: detail page 90 of UNEP publication
- Parameter:
- other: BOD protocol
- Value:
- 74
- Sampling time:
- 10 d
- Remarks on result:
- other: detail page 90 of UNEP publication
- Parameter:
- other: BOD protocol
- Value:
- 95
- Sampling time:
- 15 d
- Remarks on result:
- other: detail page 90 of UNEP publication
- Details on results:
- Measured COD was 1.99 mg O2/mg.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- In aerobic conditions using adapted wastewater from domestic sewage, degradation was 74% after 5 days rising to 95% by day 15 and in similar conditions in synthetic seawater, ethanol was 45%
degraded after 5 days rising to 75% by day 20 (Price, 1974). Biodegradation in a study to a MITI protocol showed degradation of 89% after 14 days (>70% after 10 days, CERI, 2004) and >90% within 10 days (Birch, 1991).
Activated domestic sludges were capable of aerobically oxidizing ethanol, as measured by BOD, which was 37.3% of maximum after 1 day (Gerhold, 1966).
Reference
Description of key information
As a UVCB, this mother tincture (MT) is a mixture of several components. All major constituents of TM are readily biodegradable :
- Water is biodegradable as such
- Ethanol is readily biodegradable at 74% after 5 days rising to 95% by day 15 (source OECD SIDS).
Therefore, the MT can be considered as a readily biodegradable UVCB.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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