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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29-Mar to 07-May-2019
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Remarks:
Hess. Ministerium fur Umwelt, ländlichen Raum und Verbraucherschutz, Wiesbaden, Germany
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5-bis(difluoromethyl)-1H-pyrazole
EC Number:
814-072-3
Cas Number:
77614-79-0
Molecular formula:
C5H4F4N2
IUPAC Name:
3,5-bis(difluoromethyl)-1H-pyrazole
Test material form:
solid

Results and discussion

Water solubilityopen allclose all
Water solubility:
42.3 g/L
Temp.:
20 °C
pH:
7
Water solubility:
44.7 g/L
Temp.:
20 °C
pH:
5
Details on results:
The solubility at pH 9 could not be determined due to the low stability of the test item at this pH.

Applicant's summary and conclusion

Conclusions:
The water solubility of the test item in distilled water was determined to be 42.3 g/L at pH 7 (20 °C) and 44.7 g/L at pH 5 (20 °C) according to OECD 105.