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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Remarks:
Sample sent to Vanta Bioscience Limited, K2B, 11th Cross Street, SIPCOT Industrial Complex, Gummidipundi- 601 201, Tamil Nadu, India
Type of information:
experimental study
Adequacy of study:
key study
Study period:
99 days
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine
EC Number:
921-112-4
Molecular formula:
C53H91N7O11
IUPAC Name:
N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine
Test material form:
solid: particulate/powder

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
72 h

Test conditions

Hardness:
22-22.3 °C
pH:
8.0 - 8.2

Results and discussion

Effect concentrations
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
>= 32.85 - <= 43.25 mg/L
Nominal / measured:
nominal
Conc. based on:
act. ingr.
Basis for effect:
growth rate
Remarks on result:
other: No Growth rate and yield of Pseudokirchneriella subcapitata during the 72 hours exposure period

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The Growth Inhibition value i.e. ErC50 value for N-(3β-hydroxyolean-12-en-28-oyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-Serine in fresh water unicellular green algae Pseudokirchneriella subcapitata at 72hrs exposure period is estimated to be 38.05 mg/L.The Study is performed as per OECD Guideline for testing of Chemicals Section 2, No. 201.