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EC number: 500-013-6 | CAS number: 9004-78-8 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on the properties of the indvidiual constituents of the substance
Data source
Reference
- Reference Type:
- other: expert assessment
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- An assessment was conducted based on the properties of the indvidiual constituents of the substance.
- GLP compliance:
- no
- Test type:
- other: Assessment based on the properties of the indvidiual constituents of the substance
- Limit test:
- no
Test material
- Reference substance name:
- Phenol, ethoxylated
- EC Number:
- 500-013-6
- EC Name:
- Phenol, ethoxylated
- Cas Number:
- 9004-78-8
- Molecular formula:
- not applicable - the substance is a multiconstituent substance
- IUPAC Name:
- 2-phenoxyethan-1-ol
- Test material form:
- liquid
Constituent 1
Results and discussion
Effect levels
- Remarks on result:
- other: An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated should be classified as Acute Tox 4; H302.
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Conclusions:
- An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated should be classified as Acute Tox 4; H302.
- Executive summary:
The Acute Oral Toxicity of Phenol, ethoxylated was assessed based on the available information on its constituents.
2-phenoxyethanol is associated to a Harmonised Classification as Acute Tox 4; H302, which was confirmed during the REACH Registration of the substance.
2-(2-phenoxyethoxy)ethanol was concluded not to meet the criteria for classification for this endpoint based on available experimental data on the substance.
Considering the structural similarities between the constituents of Phenol, ethoxylated, and in the absence of experimental data on the substance, 2-[2-(2-phenoxyethoxy)ethoxy]ethanol is not expected to be toxic following an acute exposure via the oral route.
While it can be concluded according to the CLP Regulation that Phenol, ethoxylated does not meet the criteria for classification as toxic following an acute oral exposure, it is suggested to classify the substance as Acute Tox 4; H302 to compensate the lack of information on one of the constituents of the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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