Registration Dossier
Registration Dossier
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EC number: 201-051-3 | CAS number: 77-71-4
Endpoint summary
Administrative data
Description of key information
The substance is predicted not to be corrosive to skin by the expert-based model.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation / corrosion, other
- Remarks:
- ToxTree
- Type of information:
- other: expert system based on decision tree approach
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Remarks:
- ToxTree
- Justification for type of information:
- Documentation about the justification is provided in attachment (See Supporting information). The reliability assessment of the prediction is presented in the attached document as well (QPRF).
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ECHA guidance on information requirements and chemical safety assessment Chapter R.6: QSARs and grouping of chemicals.
- Specific details on test material used for the study:
- O=C1NC(=O)C(N1)(C)C
- Irritation / corrosion parameter:
- other: ToxTree
- Run / experiment:
- Not corrosive to skin
- Conclusions:
- The substance is predicted to be NON-corrosive to skin.
Reference
Additional information
Justification for classification or non-classification
Although the prediction can exclude the classification of the molecule for skin corrosion, data available are deemed to be inconclusive to exclude the classification as Skin Irrit. 2 in accordance with CLP regulation.
No reliable data are available for eye irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
