Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 258-296-4 | CAS number: 53018-24-9
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 September 2018 to 23 October 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 0.135 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1 µg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- >= 6.5 - <= 7
- Details on results:
- Preliminary Test
- The content of test material dissolved in the water sample was 0.200 g/L.
Main Study
- The maximum difference of the concentrations determined in the 24, 48 and 72 hour test samples was ≤ 15 %. Based on this, the water solubility of the test material is given as the mean value of the analysed concentrations.
- No test material was detected in the pre-treated sample from the blank water mixture. - Conclusions:
- Under the conditions of this study, the water solubility of the test material at 20 °C was 0.135 g/L.
- Executive summary:
The water solubility of the test material was investigated in accordance with the standardised guidelines OECD 105, EU Method A.6 and OPPTS 830.7840, under GLP conditions.
The flask method was applied for the determination of the water solubility of the test material. The pH of the aqueous samples was between 6.5 and 7.0.
Under the conditions of this study, the water solubility of the test material at 20 °C was 0.135 g/L.
Reference
Table 1: Water Solubility of the Test Material
Stirring Time (hours) |
Analysed Concentration (g/L) |
Mean (g/L) |
Maximum Difference (%) |
pH |
24 |
0.139 |
0.135 |
10 |
6.5 |
48 |
0.140 |
6.9 |
||
72 |
0.126 |
7.0 |
Description of key information
Under the conditions of this study, the water solubility of the test material at 20 °C was 0.135 g/L.
Key value for chemical safety assessment
- Water solubility:
- 0.135 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test material was investigated in accordance with the standardised guidelines OECD 105, EU Method A.6 and OPPTS 830.7840, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
The flask method was applied for the determination of the water solubility of the test material. The pH of the aqueous samples was between 6.5 and 7.0.
Under the conditions of this study, the water solubility of the test material at 20 °C was 0.135 g/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
