Registration Dossier
Registration Dossier
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EC number: 290-179-3 | CAS number: 90082-87-4 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Prunus domestica L. Rosaceae.
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08.October 2018 - 10.October 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Plum, ext.
- EC Number:
- 290-179-3
- EC Name:
- Plum, ext.
- Cas Number:
- 90082-87-4
- Molecular formula:
- not applicable
- IUPAC Name:
- Extract obtained from fruits of Prunus domestica L. Rosaceae
- Test material form:
- liquid
- Details on test material:
- - Physical appearance: Blackish brown to dark brown liquid
- Storage conditions: At room temperature
Constituent 1
- Specific details on test material used for the study:
- Name (as stated in the report): Plum Concentrate A-270
Batch: DU00645869
Expiration date: April 19, 2019
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Key result
- Type:
- log Pow
- Partition coefficient:
- <= 1.1
- Temp.:
- 25 °C
- pH:
- 7
Applicant's summary and conclusion
- Executive summary:
The Partition Coefficient n-octanol/water of Vetynal Extra was determined by the Reverse Phase High Performance Liquid Chromatographic Method according to the OECD Guidelines for Testing of Chemicals, Method No. 117.
The result is:
Partition coefficients n-octanol/water of Plum concentrate A-270 is
log Pow<= 1.1*
*peak outside the calibration domain
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