Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: 92/69/EWG, B.3; OECD 402
GLP compliance:
yes
Limit test:
yes

Test animals

Species:
other: rat, Wistar Hsd Cpb:WU (SPF)

Administration / exposure

Type of coverage:
occlusive
Vehicle:
other: Cutiplast steril
Duration of exposure:
24 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels:
Keine systemische Wirkung.

"ENGLISH"

no systemic effect.
Gross pathology:
Effects on organs:
Die pathologische Untersuchung am Ende der Studie erbrachte
keine Veränderung, die auf einen prüfsubstanzspezifischen
Effekt hinweisen.

"ENGLISH"

The pathological examination at the end of the study showed
no change, which refer to a test-substance-specific effect.
Other findings:
Signs of toxicity (local):
Keine Reizwirkung oder sonstige Effekte.

"ENGLISH"

no irritant or other effects.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU