Registration Dossier
Registration Dossier
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EC number: 424-650-3 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- The used method refers to the Directive 92/69 published in the
Official Journal of European Community No. L 383 A/5 of
29/12/1992 (method A.8. - section 1.6.2.). - GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- gas chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.8
- Temp.:
- 25 °C
- Remarks on result:
- other: Determined using the water solubility result from laboratory conducting ecotoxicological testing (8 mg/L)
- Type:
- log Pow
- Partition coefficient:
- > 1.7
- Temp.:
- 25 °C
- Remarks on result:
- other: The water solubility value was determined as <10 mg/L. Therefore it was not possible to determine the precise log Kow (estimated >1.7)
- Conclusions:
- The partition coefficient (log Kow) was determined to be 1.8 based on a water solubility value of 8 mg/L
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- July 27 1995
- GLP compliance:
- not specified
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- ca. 3.47
- Temp.:
- 24 °C
- Remarks on result:
- other: pH not stated
- Conclusions:
- The log Pow was determined to be ca. 3.47 under the conditions of the test.
Referenceopen allclose all
Description of key information
Two studies were available to assess the partition coefficient of the substance. Each study used the flask method and the Log Kow was determined to be between 1.7 and 3.47. The conservative value of 3.47 is used in the chemical safety assessment.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.47
- at the temperature of:
- 24 °C
Additional information
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