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Diss Factsheets
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EC number: 206-887-2 | CAS number: 393-52-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 1999
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-fluorobenzoyl chloride
- EC Number:
- 206-887-2
- EC Name:
- 2-fluorobenzoyl chloride
- Cas Number:
- 393-52-2
- Molecular formula:
- C7H4ClFO
- IUPAC Name:
- 2-fluorobenzoyl chloride
Constituent 1
- Specific details on test material used for the study:
- 2-Fluorobenzoyl-Chloride / 393-52-2 / 206-87-2
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- In the pre-experiment to the solubility of the test item, its half-life in test water was determined to be less than 1.5 hours. After 20 hours, the substance has been converted to the corrisponding 2-Fluorobenzoic Acid. Therfore, according to international recommendations for substances with a hal-life less than 4 hours, the breakdown product of the parent substance was tested for its toxicity.
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Young daphnids (6-24 hours old) bred in the laboratories under identical temperature and light conditions as in the tests. The cultivation is performed in reconstituted water of identical quality as the water used in the tests.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 250 mg/l
- Test temperature:
- room temperature
- pH:
- 3.3 after the 24-hour stirring period; adjusted to 8.0 with 1M NaOH
- Dissolved oxygen:
- At the start and and the end of the tests the oxygen concentrations were at least 8.2 mg/l.
- Nominal and measured concentrations:
- nominal concentration 100 mg/l
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Details on results:
- The degradation product of the test item has no toxic effect on the daphnids up to a nominal concentration of 100 mg/l. After the 24-hr stirring period the mean concentration of FBA in the test medium corresponded to a FBC concentration of 99 mg/l, demonstrating the complete transformation of the test item to its breakdown product within the 24-hr stirring period. At the end of the test the FBA concentration corresponded to 84 mg FBC/l. Based on the measured concentration of FBA at the start and the end of the incubation period the concentrations ranged from 99 to 84% of the nominal concentration. The resuls are based on the nominal concentrations.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- It was shown that the breakdown product of 2-fluoro benzoyl chloride has no toxic effect on daphnids up to a concentration of nominal 100 mg FBC/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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