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EC number: 245-044-3 | CAS number: 22504-50-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Remarks:
- toxicity control from ready biodegradation test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Source of inoculum/activated sludge: Liede STP of Guangzhou
- Preparation of inoculum for exposure: coarse particles were removed; sludge was washed with mineral medium, after sedimentation, sludge was resuspended in mineral medium
- Pretreatment: none
- Concentration of sludge: 4.0 g dry solid/L - Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 28 d
- Nominal and measured concentrations:
- 31 mg/L
- Details on test conditions:
- TEST CONDITIONS
- Composition of medium: potassium phosphate buffer solution with Ca, Mg, and Fe added
- Test temperature: 22+-2 °C
- Suspended solids concentration: 30 mg/L
TEST SYSTEM
- Number of culture flasks/concentration: 2
SAMPLING
- Sampling frequency: Days 2, 5, 7, 11, 14, 19, 25, 29
- Sampling method: Ba(OH)2 trap
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Toxicity control: yes - Duration:
- 14 d
- Dose descriptor:
- IC10
- Effect conc.:
- 31 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Details on results:
- Toxicity control (14 d): 75.4% degr.
- Validity criteria fulfilled:
- yes
- Conclusions:
- no inhibition of activated sludge respiration at 31 mg/L
- Executive summary:
The biodegradation of GDMP was investigated over a 28-day period in a CO2 Evolution Test according to OECD guideline 301 B. The test medium was inoculated with activated sludge from a sewage treatment plant (secondary of Liede Sewage Treatment Plant of Guangzhou). The rate of degradation was monitored by measuring the carbon dioxide produced over the 28-d period. The test item was tested with a concentration of 31 mg/L in duplicates, corresponding to a carbon content (TOC) of 12.3 mg C/L in the test vessels. The biodegradation of the test item was followed by titrimetric analyses of the quantity of CO2 produced by the respiration of bacteria. The degradation was finished on day 28 by acidification, the last titration was made on day 29. After the soluble CO2 was turned out over a period of 24 h.
The percentage CO2 production was calculated in relation to the theoretical CO2 (ThCO2) of the test item. The biodegradation was calculated for each titration time.
To check the activity of the test system sodium benzoate was used as functional control. The percentage of degradation of the functional control reached the pass level of 60 % after 10 days.
In the toxicity control containing both test and reference item a biodegradation rate of 75.4% occurred within 14 days. The biodegradation of the reference item was not inhibited by the test item in the toxicity control.
Reference
Description of key information
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 31 mg/L
Additional information
The biodegradation of GDMP was investigated over a 28-day period in a CO2 Evolution Test according to OECD guideline 301 B. The test medium was inoculated with activated sludge from a sewage treatment plant (secondary of Liede Sewage Treatment Plant of Guangzhou). The rate of degradation was monitored by measuring the carbon dioxide produced over the 28-d period. The test item was tested with a concentration of 31 mg/L in duplicates, corresponding to a carbon content (TOC) of 12.3 mg C/L in the test vessels. The biodegradation of the test item was followed by titrimetric analyses of the quantity of CO2 produced by the respiration of bacteria. The degradation was finished on day 28 by acidification, the last titration was made on day 29. After the soluble CO2 was turned out over a period of 24 h.
The percentage CO2 production was calculated in relation to the theoretical CO2 (ThCO2) of the test item. The biodegradation was calculated for each titration time.
To check the activity of the test system sodium benzoate was used as functional control. The percentage of degradation of the functional control reached the pass level of 60 % after 10 days.
In the toxicity control containing both test and reference item a biodegradation rate of 75.4% occurred within 14 days. The biodegradation of the reference item was not inhibited by the test item in the toxicity control.
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