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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Not assignable data from the SIDS report on Long Chain Alcohols

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed
Year:
2006

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Various tests on inhibition of bacterial cell growth. Pseudomonas putida: DIN 38412, Teil 27 (Bacterial oxygen consumption test)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetradecanol
EC Number:
204-000-3
EC Name:
Tetradecanol
Cas Number:
112-72-1
Molecular formula:
C14H30O
IUPAC Name:
tetradecan-1-ol
Test material form:
not specified
Details on test material:
Not specified.

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
not specified
Details on test solutions:
In some tests a vehicle was used (e.g. ethanol) in others the test substance was added as such.

Test organisms

Test organisms (species):
other: Streptococcus mutans MT 5091; Pseudomonas putida; Tetrahymena pyriformis; Clostridium botulinum; Mycoplasma gallisepticum; Mycoplasma pneumoniae; Streptococcus mutans; Candida 107; Candida tropicalis; Saccharomyces carlsbergensis

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Remarks on exposure duration:
Test duration varied from 30 minutes (Pseudomonas putida) to 144 hours (cell growth inhibition tests).

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
other: Minimal Inhibitory Concentration
Effect conc.:
1.56 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: Species: Streptococcus mutans MT 5091
Duration:
30 min
Dose descriptor:
other: EL0
Effect conc.:
10 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate
Remarks on result:
other: Species: Pseudomonas putida
Duration:
48 h
Dose descriptor:
NOEC
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: No effect at level of saturation (no loading rate specified), Species: Tetrahymena pyriformis
Dose descriptor:
other: Minimal Inhibitory Concentration
Effect conc.:
0.6 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: No data on duration, Species: Clostridium botulinum
Duration:
144 h
Dose descriptor:
NOEC
Effect conc.:
13.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: Species: Mycoplasma pneumoniae
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
> 2.7 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: Species: Streptococcus mutans
Duration:
72 h
Dose descriptor:
EC0
Effect conc.:
82.4 g/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth inhibition
Remarks on result:
other: Species: Candida 107; Candida tropicalis; Saccharomyces carlsbergensis

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
In general, tetradecanol has no effect on the activity or growth of microorganisms at levels above the water solubility.