Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 947-785-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: experience in production
- Adequacy of study:
- key study
- Study period:
- before 1998
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
- Type of study / information:
- Internal report of EHS department from former MeadwestVaco (now Ingevity) about skin irritation reports in production.
- Endpoint addressed:
- skin irritation / corrosion
- eye irritation
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Individual reports from workers in production, working in the production facility where fatty acids, tall oil, reaction products with maleic acid and triethylenetetramine are manufactured. Following independent reports from workers in a weight of evidence approach applying the precautionary principle, the substance was considered as an irritant to skin, eyes and respiratory tract and appropriate measures were taken to protect workers from exposure. As a result, reportings on irritations reduced significantly.
- GLP compliance:
- no
Test material
- Reference substance name:
- Fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine, polyamido-amine
- Molecular formula:
- UVCB
- IUPAC Name:
- Fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine, polyamido-amine
- Reference substance name:
- Fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine, imido - amidoamine
- Molecular formula:
- UVCB
- IUPAC Name:
- Fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine, imido - amidoamine
- Reference substance name:
- Fatty acids, tall oil, reaction products triethylenetetramine.
- Molecular formula:
- UVCB
- IUPAC Name:
- Fatty acids, tall oil, reaction products triethylenetetramine.
- Test material form:
- liquid: viscous
- Remarks:
- Dark viscous liquid
Constituent 1
Constituent 2
Constituent 3
- Specific details on test material used for the study:
- Measures were adopted following incident reports by workers for the reaction product "fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine" but it remained unclear whether the finding were associated with the substance as such or eventually also with starting materials such as maleic anhydride and triethylenetetramine, both knowingly being skin and eye corrosives.
Method
- Ethical approval:
- not applicable
- Details on study design:
- Reports from workers working in production facility, handling the substance, collected by EHS department and analysed for improvement of handling procedures and risk management measures to be adopted.
- Exposure assessment:
- not specified
- Details on exposure:
- The reaction to produce the substance takes place at elevated temperatures where the starting materials and resulting reaction mass are molten. Although the reaction as such takes place in closed vessels, the material is drummed of after the reaction as hot melt, solidifying in transport containers, which results in possibility for exposure of workers to the substance and its vapours.
Results and discussion
- Results:
- A number of workers informed site management about skin irritations and in a very few cases also a diffuse eye irritation and irritation of the throat, when manufacturing the material. As workers do not only handle the substance "fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine", but also the starting materials maleic anhydride and triethylenetetramine, both knowingly skin and eye corrosives, a clear assignment for irritating effects for a particular substance could not be made. As effects were also observed when drumming of the material following the reaction, where maleic anhydride and triethylenetetramine have mostly reacted, a precautionary approach was taken to classify the final product "fatty acids, tall oil, reaction products with maleic anhydride and triethylenetetramine" as skin, eye and respiratory irritant, provide workers with personal protective equipment and install improvements of the local exhaust ventilation in the area where the material is drummed of as hot melt. These measures were seconded by specific activity training of workers on use of PSE and ways of handling the substance. Following the implementation of risk management measures, incidence reports reduced significantly. Therefore, in a precautionary approach, the substance since then is classified as skin and eye irritant, category 2, as well as respiratory irritant (STOT SE category 3, H335).
Any other information on results incl. tables
All personal records of worker are considered confidential and names of workers and details allowing to track back individuals are not disclosed (only known to site EHS department and medical officer in confidence).
Applicant's summary and conclusion
- Conclusions:
- Based on incidence reports from workers in production facilities, in a precautionary approach, the substance is classified as skin and eye irritant, category 2 (H315 and H319) and as respiratory irritant (STOT SE 3, H335).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.