Registration Dossier
Registration Dossier
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EC number: 812-490-0 | CAS number: 1312943-21-7
Endpoint summary
Administrative data
Description of key information
No experimental bioaccumulation data are available for MDI category substances. Although the predicted log octanol-water partition coefficient (log Kow) data indicate constituents of MDI annex VIII and above substances have the potential to bioaccumulate, predicted bioconcentration factors (BCF) suggest otherwise. The results of the Tier 1 BCF screening calculations (BCFBAF v2.01) indicate that representative components of all substances have predicted BCF values <2000 L/kg based on regression-based estimates, except for one consitituent in one substance with a BCF of 16900 L/kg.
MDI category substances only occur in a grease base designed to minimise leaching of the thickener. As the log octanol-water partition coefficient are typically predicted to be above 6, they are expected to reside within the grease base oil matrix and as such, the levels of exposure will be minimal and bioaccessibility will be restricted (as discussed further in Section 5.6 of IUCLID). On the basis of the information and data provided, MDI category members are not expected to be bioaccumulative.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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